POLLUTION. The world health organization confirms that pollution is the world s biggest environmental health risk.

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1 Moving ideas by Provital Group

2 Moving ideas by Provital Group OUTDOOR INDOOR POLLUTION The world health organization confirms that pollution is the world s biggest environmental health risk. The increasing number of people living in polluted environments is a real concern Pm 2.5 are very small particle pollutants found in the air that cause free radicals and oxidative stress that ages the skin Pm2.5 are emited by burning fuels, tobacco smoke, cooking,... EFFECTS ON HAIR itching dandruff hair loss dryness/ frizz loss of volume loss of colour 9% of visible aging is caused by environmental factors like sun exposure and pollution EFFECTS ON SKIN dull skin sensitization pigment spots wrinkles yellowing overall aged appearance Keracyn and Pronalen Bio-protect are two natural actives that work as a shield against environmental damages Keracyn TM Pronalen Bio-protect They defend skin and hair from outdoor and indoor pollutants avoiding premature extrinsec aging Natural Source

3 Moving ideas by Provital Group Keracyn TM / Hair Care Ex vivo efficacy - Protect FLUORESCENCE (Protect),12,1,8,6,4,2 Untreated T=h UV irradiated -62% Keracyn+UV Tresses are treated with Keracyn TM at 2% and afterwards they are 2 hours under radiation in a solar simulator at 25 W/m 2. The more fluorescence, the more damage. Ex vivo efficacy - Repair FLUORESCENCE (Repair) Tresses are 2 hours under radiation and afterwards treated with Keracyn TM at 2%. The more fluorescence, more free-radicals. Repairing effect of Keracyn TM. Cuticle looks smoother and more uniform after treatment with Keracyn TM. Keracyn TM protects and repairs the hair from the damage caused by environmental factors to keep it beautiful and healthy.,14,12,1,8,6,4,2 Untreated T=h UV irradiated -9% Keracyn+UV Irradiated hair Irradiated hair Irradiated hair + Keracyn TM Irradiated hair + Keracyn TM

4 Pronalen Bio-protect / Hair Care Ex vivo efficacy - PM 2.5 pollution protect PM 2.5 left on hair Water Placebo Bio-Protect A standardized amount of microparticles is applied to a 2 cm x 2 cm area of the hair tress, using 2 blond hair tresses for each treatment (water, placebo and active). The tresses are analyzed to assess the surface in pixels covered by the black particles. A single application of Pronalen Bio-protect at 3% significantly decreases the amount of pollution (PM2.5) that adheres to the hair fiber. Images of the hair fibers. Visible protective effect of Pronalen Bio-protect. Not treated Placebo P. Bio-Protect Pronalen Bio-protect / Skin Care In vitro efficacy - Pollutant effect of heavy metals Study of the oxidising effect and the formation of free radicals on the cell membrane due to heavy metals: Hg and Cd. In the cells, heavy metals, from contamination, inactivate numerous enzymatic systems and intervene in processes of lipoperoxidation, destabilising the cellular membranes. % Cell viability protection (%) 91% 34% 54% 65% Pb Cd Hg Zn Protective action against Hg 17 % Protective action against Cd 41 % The cytotoxicity of the aforementioned metals was studied on cell cultures of human facial tissue fibroblasts and the variation produced in cell viability was evaluated in the presence of Pronalen Bio-protect under exposure to heavy metals.

5 Pronalen Bio-protect / Skin Care In vitro efficacy - Pollutant effect of gases The protective effect of Pronalen Bio-protect was evaluated with an ATP dosage by bioluminescence. This test was undertaken on keratinocytes in the presence of pollutant gases, cigarette smoke and car exhaust Pronalen Bio-protect has a protective effect against the pollutant action of gases. The control was almost doubled by Pronalen Bio-protect. 1 Gas control Gas +.2mg/ml BP Gas +.5mg/ml BP In vivo efficacy 2 volunteers Skin type origin: Chinese Age: from 35 to 65 years Gender: female Specific criteria: all skin types on the face, presenting a dull complexion and presenting darks spots on the face, with one pigmentary spot well defined on each half-face. Protocol Two applications per day during 28 days. Placebo in half of the face and the active, Pronalen Bio-protect 3%, in the other half of the face. Study place Wuhan (China) city with high levels of pollution. D D28 Pronalen Bio-protect reduces sebum secretion and unifies skin tone by reducing spots intensity. D D28 Detox benefits Luminosity improvement Spot area reduction Sebum reduction Yellowing minimization

6 Keracyn TM Global protection and resistance for a shiny and healthy hair Technical specifications keracyn TM 734 PROPERTIES ACTIVES MOLECULES APPEARANCE SOLUBILITY Cuticle protection role Avoids degradation of hair components Antioxidant that safeguards hair fiber from aggressions Standardized in hydroxycinnamic acids Transparent liquid Pale brown - brown color Soluble in aqueous solutions Hair strengthening and intensive repairing products Styling and fixing hair products Hair repairing products to use after chemical and/or thermic hair treatments Specific products for a bright radiance INCI / PCPC Formulation Detox Hair Sleeping Pack % (w/w) A Aqua (Water) Panthenol Ethylhexylglycerin Citric Acid, Aqua (Water) Sodium Methylparaben Glyceryl Caprylate, Glyceryl Undecylenate Acrylates/C1-3 Alkyl Acrylate Crosspolymer B Ama-leaf Keracyn TM Pronalen Bio-protect ZNSN RECOMMENDED DOSE.5-5 % Pronalen Bio-protect C Aqua (Water), Sodium Hydroxide 1.62 Skin and hair protection against environmental pollution Hair and skin cosmetic protector against environmental and urban pollution Primers and make up for an added value Hair products for daily use Technical specifications Pronalen Bio-protect TM 7523 PROPERTIES ACTIVES MOLECULES APPEARANCE Hair and skin protection against environmental and urban pollution Standardized in ginsenosides, pectines and inositol hexaphosphate Turbid liquid Pale brown Potassium Sorbate Sodium Benzoate Pronalen Bio-Protect ZNSN Xeradin Açai Eco Goji Eco Vitasource Agascalm B Sepiplus 4 1,3 Butylene Glycol Lexgard Natural Actigum VSX 2 D.C. RM SOLUBILITY RECOMMENDED DOSE Soluble in aqueous solutions.5-5 % Formulation Skin Saver Detox DD Serum INCI / PCPC % (w/w) A Aqua (Water) Dissolvine GL-47-S.2 C KF Daitodispersion Ti-45 (TiO2) 3. Daitodispersion Zn-7-3 (ZnO) D SH219 E HPW-YP-SP HPW-RSP-8P HPW-BP-8P HPW-T-MP P F Lactic Acid, Aqua (Water) 1.85 G Parfum (Fragrance).2 V1-215