GENERAL BIOLOGY I. Lecture Schedule WEEK LECTURES TOPIC PAGES

Transcription

1 GENERAL BIOLOGY I Course Syllabus for Bio ogy 1101 Coordinators: Profs. D.M. Bakewicz, J. Seto and A. Zameer Textbook: BIOLOGY by Mader& Wind especht, 12th Ed., McGraw-Hi, 2015 Laboratory Manual: Bio ogy Laboratory Manua for Genera Bio ogy I, Edited by Bakewicz, Seto, Zameer, McGraw-Hi 2013 ISBN-13: Course Description: The fundamenta princip es of bio ogy focus on topics inc uding taxonomy, structure, nutrition, reproduction, heredity, deve opment and evo ution. The concepts of mo ecu ar bio ogy and DNA fingerprinting using representative p ants and anima s are introduced. The course a so inc udes the use and care of the microscope. Lecture Schedule WEEK LECTURES TOPIC PAGES I 1. BASICS Introduction to the Course Definition, Characteristics and Hierarchy of Life 1-6 Scope of Eco ogy: habitat, Popu ation, Community, 837 Ecosystem 6-9 The Scientific Method Evo ution and C assification Systematics, taxonomy, phy ogeny THE ORIGIN & EVOLUTION OF LIFE Darwin & Evo ution The Origin of Life The Geo ogica Time Sca e Ce u ar History 7-8 Kingdoms and Domains II 3. INORGANIC CHEMISTRY I Definition, C assification and Properties of Matter 20 Atomic Structure 21 The periodic Tab e Isotopes 22 E ectrons and Energy 23 Energy Chemica Reactions: Exergonic and endergonic 103 Activation Energy 106 Oxidation and Reduction INORGANIC CHEMISTRY II E ements, Compounds, Mo ecu es and Mixtures 24 Bonds: Weak and Strong III 5. WATER & ph Importance and Properties of H 2 O Acids, Bases, ph, Buffers 30-32

2 6. ORGANIC CHEMISTRY Importance of Carbon Organic vs. Inorganic Compounds The Hydrocarbons Functiona Groups Isomers IV 7. Examination I (Lectures 1-6 inc usive) 8. MACROMOLECULES I Monomers and Po ymers Dehydration Synthesis and Hydro ysis Carbohydrates Lipids V 9. MACROMOLECULES II Proteins Nuc eic Acids ATP 52-53; Enzymes and Metabo ic Pathways CELLS The Ce Theory Methods of Studying Ce s Ce u ar Size Limitations Ce Composition Prokaryotic and Eukaryotic Ce s Ce u ar Evo ution Anaerobic and Aerobic Ce s; Endosymbiosis; Mu tice u arity; Viruses, Bacteria and Archaea VI 11. THE EUKARYOTIC CELL Eukaryotic Ce Structure and Function MEMBRANES & TRANSPORT Membrane Structure and Function Passive Transport Processes Active Transport Processes Ce Surface Modifications VII 13. Examination II (Lectures 8-12 inc usive)

3 14. ENERGY Ce s and the F ow of Energy Metabo ic Reactions and Energy Transformations Metabo ic Pathways 105 Oxidation and Reduction 109 Organe es and the F ow of Energy VIII 15. CELLULAR RESPIRATION I Ce u ar Respiration (Anaerobic) Outside the Mitochondria: G yco ysis Fermentation CELLULAR RESPIRATION II Ce u ar Respiration (Aerobic) Inside the Mitochondria: The Preparatory Reaction (Hub) Citric Acid Cyc e (TCA) E ectron Transport Chain (ETC) Metabo ic Poo IX 17. PHOTOSYNTHESIS I Photosynthetic Organisms The Process of Photosynthesis P ant as So ar Energy Converters: Light Reactions PHOTOSYNTHESIS II Dark Reactions: Ca vin Cyc e Reactions (Carbon Fixation) Other Types of Photosynthesis X 19. ASEXUAL REPRODUCTION The Ce Cyc e and Its Contro Mitosis and Cytokinesis The Ce Cyc e and Cancer Prokaryotic Ce Division SEXUAL REPRODUCTION Ha ving the Chromosome Number Genetic Variation The Phases of Meiosis Comparison of Meiosis and Mitosis The Human Life Cyc e (Spermatogenesis & Oogenesis) 21. CHROMOSOMES Changes in Chromosome Number and Structure XI 22. Examination III (Lectures inc usive)

4 23. GENETICS I Gregor Mende Mende s Law Human Genetics Disorders XII 24. GENETICS II Extending the Range of Mende ian Genetics Mu tip e A e ic Traits Incomp ete Dominance P eiotropy Po ygenic Inheritance X-Linked Inheritance Environmenta Inf uences XIII 25. DNA The Genetic Materia DNA Structure DNA Rep ication Prokaryotic versus Eukaryotic Rep ication GENE FUNCTION The Genetic Code Transcription Trans ation Structure of the Eukaryotic Chromosome XIV 27. GENETIC REGULATION Prokaryotic Eukaryotic Regu ation Through Mutations BIOTECHNOLOGY & GENOMICS DNA C oning Biotechno ogy Products Gene Therapy 250 Genomics XV 29. ANIMAL DEVELOPMENT Ear y Deve opmenta Stages Deve opmenta Processes Human Embryonic and Feta Deve opment Examination IV (Lectures inc usive)

5 LABORATOR SCHEDULE WEEK EXERCISE PAGE I The Microscope: Basic ski s 1 Stain Eukaryotic cheek ce s 13 II Chromatography 21 Separation of dye mo ecu es Measurements in Science: Metric System 23 III ph: Acids, Bases and Buffers 15 IV Bio ogica y Important Mo ecu es I: Carbohydrates & Lipids 28 V Bio ogica y Important Mo ecu es II: Proteins, Nuc eic Acids 33 VI Quantitative Determination of Proteins 39 VII Enzyme Kinetics 48 VIII Membranes and Bio ogica Transport: Diffusion and Osmosis 56 IX Ce u ar Respiration: Anaerobic and Aerobic 66 X Photosynthesis 75 XI Mitosis: Rep ication of Eukaryotic Ce s 100 Meiosis: Reduction Division and Gametogenesis 109 XII Princip es of Ge E ectrophoresis 81 Purification of DNA, Dische s Test 33 XIII DNA Fingerprinting 93 XIV Genetics Prob ems 120 XV Mende ian Genetics I: Corn 131 Mende ian Genetics II: Chi-Square 135

6 N.Y.C. College of Technology Department of Biological Sciences Course-Based Learning Outcomes and Alignment with General Education Goals Upon satisfactory completion of this course, the student will be able to: BIO1101 NYCCT Gen Ed Common Core CUNY Common Core 1. Comprehend the principles of biology. Use the arts, sciences and humanities as a forum for the study of values, ethical principles, and the physical world. Engage in an in-depth, focused, and sustained program of study. Identify and apply the fundamental concepts and methods of a life or physical science. 2. Appreciate the relationship of the other sciences to biology. 3. Understand the scientific method, its history and importance to society. 4. Acquire skills in the use of biological equipment and techniques. Understand and appreciate the range of academic disciplines and their relationship to the fields of professional and applied study. Employ scientific reasoning and logical thinking. Acquire and use the tools needed for communication, inquiry, analysis, and productive work. Apply the scientific method to explore natural phenomena, including hypothesis development, observation, experimentation, measurement, data analysis, and data presentation. Use the tools of a scientific discipline to carry out collaborative laboratory investigations. 5. Develop expertise in the written and oral expression of biological ideas. Acquire and use the tools needed for communication, inquiry, analysis, and productive work. Communicate in diverse settings and groups, using written (both reading and writing), oral (both speaking and listening), and visual means, and more than one language. Gather, analyze, and interpret data and present it in an effective written laboratory or fieldwork report. 6. Gain skill in the collection of data and in its mathematical treatment and interpretation. Derive meaning from experience, as well as gather information from observation. Understand and employ both quantitative and qualitative analysis to describe and solve problems, both independently and cooperatively. Gather, interpret, evaluate, and apply information discerningly from a variety of sources. Gather, analyze, and interpret data and present it in an effective written laboratory or fieldwork report. Identify and apply research ethics and unbiased assessment in gathering and reporting scientific data. 7. Acquire the knowledge needed for a thorough understanding of the major bioethical issues in society. Use the arts, sciences and humanities as a forum for the study of values, ethical principles, and the physical world. Understand and apply values, ethics, and diverse perspectives in personal, professional, civic, and cultural/global domains.

7 N.Y.C. College of Technology Department of Biological Sciences BIOLOGY I (BY 1101) COURSE INFORMATION MATERIALS In addition to the lecture text and the lab manual, you will need a separate notebook for lecture and lab. For the lab, you will also need pencils, a pen, and a lab coat. These supplies can all be obtained from the bookstore. WORKLOAD Considerable effort must be expended in order to satisfactorily complete the course. It is expected that you will spend at least 3 hours per week in preparation for each credit hour of course work; this is a total of 12 hours. If you are not able to devote the requisite amount of time to your studies then you should seriously reconsider your decision to take the course at this time. ATTENDANCE AND LATENESS You must attend both lecture and lab. Absences in excess of 10% of the total lecture or lab hours will result in your being dropped from the course with a failing grade (WU or unofficial withdrawal). This means that no more than 3 lecture or 2 lab absences will be tolerated. It is expected that you will be in your seat and ready to work at the start of each period. Any 2 latenesses will be considered to be equal to 1 absence. GRADING POLICY Your grade for the course is computed by adding 60% of your lecture average to 40% of your lab average. There are 4 lecture examinations which each cover one quarter of the lecture work as indicated in the outline; these are announced at least one week in advance by your instructor. 80% of your lab grade is derived from your quiz average (at least 5 quizzes). 10% of the grade will be derived from at least one full scientific lab report. The remaining 10% of your lab average is based on the quality and completeness of your lab work. ALL GRADES ARE COUNTED; NONE ARE DROPPED NOR ARE THEY CURVED. NO M AKE-UPS ARE GIVEN EXCEPT AT THE DISCRETION OF THE INSTRUCTOR PENDING SUBMISSION OF WRITTEN PROOF OF REASON FOR ABSENCE. Letter Grade Numerical Ranges A A B B B C C D F 59.9 and below

8 SUGGESTIONS You re responsible for ll m teri l, nnouncements, or ssignments mentioned in cl ss whether you re present or not. It is therefore dvis ble to write down the n me of your instructor(s), the office, phone extension nd office hours. It is lso dvised to get the n mes nd phone numbers of sever l cl ssm tes who m y be cont cted in the event th t you re bsent. Check Bl ckbo rd for nnouncements, links nd schedules from your instructor. In order to optimize your perform nce, it is strongly dvised th t you re d your lecture nd l b ssignments prior to coming to cl ss. At the end of e ch ch pter in the text nd in the l b m nu l review questions re v il ble for you to test yourself. A Student Study Guide m y be purch sed long with your text book. Tutori l help in the Resource Center is usu lly v il ble if ddition l ssist nce is needed. Online Le rning Modules (Le rnsm rt) nd study m teri ls c n be found t McGr w-hill s derbiology11. A code comes with e ch newly purch sed textbook or c n be purch sed sep r tely for further electronic tools (CONNECT). This includes: Inter ctive Activities (pr ctice quizzes, nim tions, l beling exercises, fl shc rds, etc.); Online Tutoring; Anim tions nd Anim tion Quizzes. If you encounter ny serious difficulties during the semester, it is suggested th t you m ke n ppointment with n instructor to discuss them.