36396 Steinau an der Straße COMPANY PROFILE

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1 36396 Steinau an der Straße COMPANY PROFILE Aerial Photo of DREITURM GmbH DREITURM GmbH Dr.-Rudolf-Hedler-Str Steinau an der Straße Germany Fon Fax info@dreiturm.de

2 COMPANY S HISTORY 185 YEARS DREITURM 1825 FOUNDATION IN SCHLÜCHTERN Modern soap factory - Manufacturing of soft soaps, soap bars, washing powder and soda 1930 MOVING TO STEINAU Extension of product range with household products, e.g. floor waxes 1945 NEARLY TOTAL DESTRUCTION OF THE FACTORY 1950 NEW START OF PRODUCTION 1970 FOUNDATION OF TODAY S DREITURM GMBH After the soap production had been discontinued, DREITURM became a refining factory producing a range of products in the fields: Industrial products Household products Health and body care products 1971 COMPLETE RENOVATION OF PRODUCTION CENTRE Production of liquid and semi-liquid products begins PRODUCTION AND EXTENSION OF SALES DEPARTEMENT: Contract customers Bulk consumer Export 1976 AUTHORIZATION ACCORDING TO 13 AMG Manufacturing of medicin in liquid and semi-solid form EXTENSION OF AREA PHARMACEUTICAL AND MEDICAL DEVICES Establishment of the areas Pharma I and Pharma II 1999 CERTFICATION ACCORDING TO DIN EN ISO 9001:2000 AND DIN EN ISO Manufacutring of medical devices EXTENSION AND STARTING UP OF PRODUCTION AREAS PHARMACY Establishment of the area Pharma III 2002 OUTSOURCING DIRECT MARKETING 2003 EXTENSION OF PRODUCTION AREAS: Batch capacities Filling/packing capacities CHANGE-OVER OF THE POWER SUPPLY FROM OIL TO GAS 2005 IMPLEMENTATION OF THE ERP SYSTEM NAVISION NEW ANALYTICAL LABORATORY 2006 CERTFICATION ACCORDING TO DIN EN ISO 9001:2000 AND DIN EN ISO 13485: TRANSFER OF SHARES (50%) FROM DR. RUDOLF HEDLER TO STEFAN HEDLER 2009 ACQUISITION OF SHARES FROM THE FOUNDING FAMILIES WOLF BY STEFAN HEDLER Stefan Hedler is now DREITURM's sole shareholder AUTHORIZATION FOR USING THE ECO FLOWER CERTIFICATE FOR OUR NEW DEVELOPED PRODUCTS BDIH ATTESTATION FOR THE PRODUCTION OF NATURAL COSMETICS 2010 CERTFICATION ACCORDING TO ISO 9001:2008 UND EN ISO 13485: AC:2007 NEW DEVELOPMENT LABORATORY EXTENSION OF PRODUCTION AREA (BATCH CAPACITIES) PHARMA III EXTENSION OF STORAGE CAPACITIES

3 OUR CORPORATE GUIDELINES A company defines itself essentially through its philosophy, since this is the foundation of the daily work and therefore an important element of customer satisfaction and economical success. Who we are... As a traditional, mid-sized company we are proud to be independent and autonomous family-owned. We are future-oriented, consequently investing in new technologies and rising to eco-political challenges. We set great value upon the preservation of the location, the jobs and the therewith involved existences. How we see ourselves... We are part of the society and therefore liable to a substancial corporate social responsibility. For a good cooperation we view all conversational partners - customers and colleagues - as what they are: HUMAN BEINGS. You will feel a respectful cooperation and a lived benevolence in every contact with our employees. What we have to offer... You will be convinced with the professional competence, reliability and kindness of our responsible employees. Quality, service and adherence to delivery dates are not only words, they are a fundamental commitment towards our customers. To fulfill your individual needs we offer our long-term experience and competence, combined with a very high vertical range of manufacture. One of our outstanding qualities is our flexibility; a short decisionmaking process is used to meet all of your requirements. How we measure success... Your reliance and your satisfaction are not a matter of course, we want to deserve them every day. Only a partner-like and long-term cooperation is a successful cooperation for us.

4 COMPANY S DEVELOPMENT DREITURM GmbH is a company, that distributes its body care and household products and its floor cleaners via a widespread network of specialist wholesalers. DREITURM GmbH is also a company, that works as a contract manufacturer for many companies in the pharmaceutical and cosmetic industry as well as for many large companies in the field of household cleaners and household care products. However, manufacturing medical and pharmaceutical preparations also become a significant part of the business. No matter if manufacturing according to batch or conti -processes or in modern homogenizing process plants under vacuum DREITURM is able to meet all demands. Efficient filling lines for tubes, bottles, jars also large containers we garantee an optimal production process. Our in-house research and developing laboratory, analytical laboratory, the microbiology and the packaging control are inherent parts of our quality management protocol. All our pharmaceutical production areas are continously brought up to the latest standards of technical know-how and have been equipped accordingly. It is possible to produce according to GMP, as the goods are manufactured in climate controlled and over-pressurized facilities. All this is documented under consideration of cleaning and manufacturing instructions as well as necessary in-process controls. All raw materials are supplied through an appropriate security entrance to our pharmaceutical production areas. Weighing is done under consideration of Laminarflow, which avoids a chemical and microbiological contamination. The demineralized water, used for manufacturing, becomes a pharmaceutical raw material thanks to modern technology. All formula ingredients are released under strict pharmaceutical quality checks. Utilizing production lines equipped with pharmacode reading devices provides and guarantees an optimum control. Our at the beginning of 2010 newly established Laboratory of research and development, our state of the art analytical Laboratory, our in-house microbiology and the packaging control represent the base frame of a comprehensive quality assurance system. Following our guidelines, an anticipatory orientation of our enterprise only can be ensured by ongoing investments in new technologies in the manufacturing and laboratory areas, which is on our part implemented consequently. DREITURM should be able to support its reputation and to expand its position - thanks to the considerable investments - in the following years, especially with respect to the growing internationalization of its activities.

5 CONTRACT MANUFACTURING Filling Development and formulation service Manufacture according to GMP Packing Storage and shipment just in time Permanent quality management DREITURM GmbH is a leading contract manufacturer for national and international companies. Our goal is a mutual and partner-like cooperation to achieve the best possible price-performance ratio, as well as creating a long-term relationship with our customers. Our efforts to improve quality standards always have priority. Ongoing considerable investments guarantee a high flexibility to meet unusual demands. We manufacture according to DIN EN ISO 9001 : 2008 Cosmetics and body care products according to GMP Pharmaceuticals - according to 13 AMG Medical preparations - according to DIN EN ISO : AC : 2007 Chemical technical products We develop and manufacture: Creams and toiletries, emulsions, lotions, gels, ointments, liquids, pastes, pharmaceuticals in liquid or semi-solid dosage form for oral, topic and perioral use, medical preparations, chemical-technical products, cleaning and care products, disinfection solutions. We bottle, pack, store and deliver: bottles cans and barrels tubes sachets (four cornered soft bag) jars/tins special packing Get your company slimmer and more efficient. If outsourcing is a service you want to achieve, we are your competent partner.

6 PRODUCTION Batch-area Pharma I vessel: 1 ton Becomix Batch-area Pharma III vessel: 5 ton Becomix, 2,5 ton adipose phase, 5 ton aqueous phase Protected against explosion Batch-area Pharma III vessel: 6 ton Becomix, 6 ton aqueous phase Protected against explosion

7 FILLING LINES Filling-line Rationator Crucible-filling

8 QUALITY MANAGEMENT

9 PRODUCTION PROGRAM DREITURM s production is divided into the following sections: 1. Contract manufacturing of pharmaceutical products and medical preparations as well as developing and manufacturing of cosmetic products and household cleaners for a wide range of well-reputed companies. 2. Development, manufacture and distribution of cleaners and floor care products for bulkconsumers. Capacities Batch volume Filling capacity / 8h Cosmetic 3.0 tons Hall I units Liquids batch 55.0 tons Cosmetic parterre units Ex-proof 15.0 tons Sachets units Pharmacy I 1.0 tons Cosmetic ML units Pharmacy II 1.0 tons Fluids & pastes units Pharmacy III 11.0 tons Pharmacy I units Laboratory (cosmetic) kg Pharmacy II units Laboratory (technical) 40 kg Pharmacy III units Performance data analytics and quality control IR-analysis, UV-determination GC-determination, DC-determination Density, refractive index, ph-measurement Viscosity measurement Conductance Loss of dry Ash content Determination of flash point Determination of water quality Volumetric titration Microbiological examination: bioburden, yeasts, mildews Analytical methods according to European Pharmacopoeia and German Pharmacopoeia. Monitoring of manufacturing lines with statistical control standards according to packaging material regulations.

10 REFERENCES Some of our reference customers and their products.

11 CONTACT INFORMATION DREITURM GmbH Dr.-Rudolf-Hedler-Str Steinau an der Straße Germany Fon: Fax: info@dreiturm.de Web:

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18 Bath Therapy

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