Collaboration to Insight
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1 Collaboration to Insight November 2016 HUMAN HEALTH ENVIRONMENTAL HEALTH 2015 PerkinElmer
2 Safe Harbor Statement This document and/or presentation shows current intentions regarding product features, behavior, schedules and support; these intentions may change without notice as we respond to customer requirements. Any unreleased products, services or features referenced herein are not currently available and may not be delivered on time or at all. Customers who purchase PerkinElmer informatics applications should make their purchase decisions based upon products, features, and services that are currently available.
3 Agenda Themes Workflow Solutions Getting Answers: Virtualized Data Integration and Analytics Preview of new application for Structure Activity Relationship analysis 3
4 Forces at Work in our Industry Key Market Trends (2010-Present) Complexity of customer questions increasing More data intensive assay platforms Big data technologies required to keep up with science Rapid cloud and mobile adoption Increasing R&D externalization and collaboration Worldwide data volume doubles every two years. By 2020, it will have grown to 40 zettabytes a 50x increase within 10 years Implications for our strategy Need Informatics solutions to complete customer scientific workflow Informatics increasingly important to differentiate instrument platforms Customers want more complete solutions to help answer their complex questions 4
5 Innovation Lab SCIENCE CORE CAPABILITIES ANALYTICS ARCHITECTURE Life Science Physical Science Pharma Science Clinical Development Collaboration Compliance Data Management Workflow Data Visualization Data Integration Advanced Statistics Machine Learning Modularity Security Performance Cloud Informatics The New Speed of Science
6 An Evolution of Needs Data analytics Capturing Flexible Content Documenting The Experiment All file types Signing, witnessing workflows Text string searching Organizing the Workflow Guiding data capture into specific fields Increasing consistency Guided personal workflows Collaboration Provide communication between groups Sample creation Returning reports Mining and visualizing data from across the company Data compiled from multiple experiments 6 These intentions may change without notice as we respond to customer requirements.
7 Strategy to Support Fundamental Research Workflows Research Workflow Suite Cloud enabled Integrate workflows Make What gets made Compounds Biologics Formulations Sample Prep Collaborate Decision Support Use Cases SAR Other Technology Search Analytics Decide Test What gets tested Proteins Cells Animals Analytical samples 7
8 PerkinElmer Platform Core Configurable System Components Collaboration Data Management Sample Workflow Analytics Flexible Organization Security Form Builder Flexible Test Results Test Requests Sample Management Spotfire NoSQL Data Warehousing 8
9 ELN, Search and the Larger Data Sphere Intersection of research informatics, search and business intelligence Data In Structuring Data Ingesting Data Data Out Mining and visualization Analytics Index Integration & Enrichment Structures 9 CDS Data LIMS Clinical Documents
10 Sample DMPK and Bioanalytical Workflow User Roles Browse by Protocols & Studies SD Create PK Protocol Scientist Create PK Studies Formulation Study Folder InLife Study Folder PK BA Study Folder Generate PK Report and Summit for QC Submit to CRO 10
11 Organizational Framework PK scientists are organized into groups Study Design users direct the entire DMPK studies 11
12 Formulation Initiation In Formulation Study Folder, to prepare formulation, information of dose groups and test articles can be loaded from PK protocol Load dose groups Load test articles 12
13 In vivo samples collected Any entry with completed data will light as green. Time automatically entered. 13
14 Final Data from Bioanalytical Collated 14
15 Bench level analytics for Formulation Scientists 15
16 Process Optimization Example 16
17 Project management 17
18 Data to Insight Framework Capabilities Function Perception Advanced Analytics Data Discovery Mathematical Perception Visual Perception Agility Agile Science Agile Warehousing Collaboration Assay Result Storage Structured & Unstructured Data Document & Share Flexibility Storage Cloud Mobile Backend flexibility Flexibility, Scalability & Externalization Mobile Access 18
19 PerkinElmer Signals Perspectives A system that gives you answers DATA SOURCES TECHNOLOGIES SAP Scientific Assays E-Notebook Forms Structured Data Workflow Document Stores Documentum Opentext ANSWERS Stability NoSQL Instruments Fileshares Analytics Process Control Portals 19
20 Virtual data aggregation and analytics ELN that structures data Analytics across systems Integrated text analytics 20 Scientific data visualization Integrated design of experiment Instrument data processing Natural multivariate statistics
21 Other Analytical Data Proposed Analytics Architecture Analytical Data PerkinElmer Signals Screening Data Analytical & CDS Data Formulations ELN Analytical Tests Other Experiments ELN Data Other Systems? 21 SpotFire
22 Real-time query directly in Spotfire Type-ahead to filter project list. 2. Select the project(s) of interest. 3. Signals for SAR provides real-time feedback about how many compounds are found. 22
23 Data download to customizable SAR Tables 23
24 Easily configured SAR analysis 24
25 Point-and-click chemically intelligent histograms 25
26 Rotate-able 3D scatter plot to explore chemical space 26
27 Point-and-click SAR cross-table saves hours of work 27
28 Analyze Compound series 1. Input substructures and have the found compounds tagged as compound series. 2. Those compound series tags then appear as axis options and filter options in the other windows. 28
29 Thank you Michael Swartz VP, Strategy & Commercial Joshua Bond Director, Portfolio Strategy
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