CURRICULUM VITAE. Dr. BONTHA VENKATA SUBRAHMANYA LOKESH (M.Pharm.; Ph.D.) CURRENT POSITION: Assistant Professor

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1 Dr. BONTHA VENKATA SUBRAHMANYA LOKESH (M.Pharm.; Ph.D.) CURRENT POSITION: Assistant Professor UCSI UNIVERSITY Faculty of Pharmaceutical Sciences No:1, Jalan Menara Gading, UCSI Heights, Taman Connaught, Cheras Kuala Lumpur, Malaysia PERSONAL BORN 31 st August 1970 NATIONALITY: INDIA Passport number: Z EDUCATION (1) Ph.D.,( ), AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam, India. Date of Ph.D. awarded: ( ) Dissertation: "Synthesis and Biological evaluation of some five and six membered heterocycles containing nitrogen " Supervisor: Prof. Y. Rajendra Prasad, Andhra University, Visakhapatnam, India (2) Master of Pharmacy, 1995, Andhra University College of Pharmaceutical Sciences, Majors in Pharmaceutical and Food Analysis (74.1%, Distinction, TWO UNIVERSITY awards) College of Pharmaceutical Sciences, Visakhapatnam, India Dissertation: Development of new spectrophotometric methods for the estimation of Amlodipine Besylate in formulations 1 P a g e

2 (3) Bachelor of Pharmacy, 1993, Andhra University College of Pharmaceutical Sciences, Majors in Pharmaceutical Sciences, Visakhapatnam, India Total Experience: 22 years (1995-Present) CURRENT POSITION 2002-PRESENT(15 years), Assistant Professor, Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia Faculty Chair-Regulations, Assessment and Examinations (RAE) Vice Chair-QAE, Head-Faculty Examination Board (FEB) PAST POSITIONS (4 years), Lecturer Department of Pharmaceutical Chemistry, School of Pharmacy Addis Ababa University, Addis Ababa, Ethiopia, Africa (Under UNDP contract) (3 years), Group Leader- Analytical Research and Development, Cheminor Drugs Limited Pharma Division (Dr. Reddy s group of companies), Hyderabad, India CURRENT PROFESSIONAL ACTIVITIES Faculty Management Board member, Member, Faculty Research and Scholarly activity, Vice Chair-Quality, Assessment and Examinations (QAE), Head-Faculty Examination Board Life member of Association of Pharmacy Professionals, India (APP/INT/LM-111H/15) HONORS The prize awarded for obtaining highest marks in any M. Pharmacy specialization - Pharmaceutical and Food Analysis, Pharmaceutical Chemistry, Pharmaceutical Technology, Pharmacognosy, Pharmacology and Pharmaceutical biotechnology 2 P a g e

3 The prize awarded for obtaining highest marks in annually at the convocation while passing M. Pharmacy degree examination at the first appearance with Pharmaceutical and food analysis specialization, secured highest number of marks in the exam of I & II years taken together. Long Service Award was given recently given for my outstanding contributions to University and Faculty for the past 15 years since 2002 by the Chancellor as well as Founder of the University. GRANTS ACHIEVED Research project completed (Research Grants Scheme, CERVIE, UCSI UNIVERISTY) Formulation and characterization of Bioconjugated rapamycin nanoparticles Research fund: RM 80, Grant No: Proj-FPS-In-002 Status: Completed Undergraduate Student Project in 2008 (FACULTY GRANT) Development of Dissolution method for valsatran tablets allied external project with Pharmaniaga research center (A leading Pharmaceutical company in Malaysia, Kuala Lumpur) Research fund: RM 1500 Status: Completed Current Research project (on going) (Cluster Research Grant Scheme, CERVIE, UCSI UNIVERSITY) Investigations of Termitomyces heimi and Lignosus rhinoceros Extracts and Laccases for Bio-Bleaching and Quoru- Sensing Inhibition Co-researcher and Research fund approved: RM 133,000 Project completed Postgraduate student project supervision(approved) September 2015-March 2016 Status: Completed Comparative analysis of Reversed Phase HPLC and ATR-FTIR methods for Dapagliflozin in Pharmaceutical Preparations 3 P a g e

4 Current research project approved Status: ongoing; September 2017-March 2019 Forced Degradation Studies and Development of Stability Indicating Assay of flibanserin in API Fund: RM JOURNAL ARTICLES 1. Lokesh BVS*, Reddy MN, Shankar DG and Sridhar K. (1996) Extractive spectrophotometric determination of. Amlodipine. The Eastern Pharmacist, 39, 458: Lokesh B V S* and Narayana R M (1999) Colorimetric determination of amlodipine. Ethiop Pharm Journal 17, Affordability and Differential drug pricing: The Malaysian Perspective, Z U Baber, M.Izham, M.Ibrahim and B V S Lokesh (2003), INTRUD News, Volume 13, 1:p21 4. Lokesh B V S* and S.Raghava Naidu(2007), New dissolution method for the evaluation of enalapril maleate tablets using ph 7.2 phosphate buffer in vitro and determination of its content by validated UV Spectrophotometric method UCSI JASA, 2: B V S Lokesh* (2012) An overview on the lack of proper evaluation and standardized analytical methods of currently marketed herbal products- a remedial approach, International Journal of Research in Pharmacology and Pharmacotherapeutics, issue 1: Lokesh B V S* and Palanirajan Vijayraj Kumar(2014) Synthesis and Characterization of Polymeric conjugated sirolimus on MCF-7(Estrogen positive) and MDA MB 231(estrogen negative) Breast Cancer Cell lines International Journal of Pharmacy, 4(1):42-51.[impact factor: 2.142(2014)] 7. Palanirajan Vijayaraj Kumar and Bontha Venkata Subrahmanya Lokesh Designing and In-Vitro Characterization of Micelle Forming Amphiphilic PEGylated Rapamycin Nanocarriers for the Treatment of Gastric Cancer Current Drug Delivery (2014), Volume 11 - Number 5, Pp: ; DOI: / (Impact factor: 2.248) (SCOPUS INDEXED) 8. Kiran, T.N.R., Alekhya, Ch.S., Lokesh, B.V.S., Latha, A.V.S.M., Prasad, Y.R. and Mounika, T.N. (2015) Synthesis, Characterization and Biological Screening of Ferulic Acid Derivatives. Journal of Cancer Therapy, 6, (Impact factor: 0.55) (Google Scolar) 4 P a g e

5 9. Lokesh B V S * and Kumar P V Enhanced Cytotoxic Effect of Chemically Conjugated Polymeric Sirolimus against HT-29 Colon Cancer and A-549 Lung Cancer Cell Lines J Pharm Drug Deliv Res (2015), 4:2 (Impact factor: 1.846) (Google Scholar) 10. Sabbagh B, Lokesh B V S*, Akowuah G A., (2017), Validated RP-HPLC and UV- Spectroscopy Methods for the Estimation of Dapagliflozin in Bulk and in Tablets, Indian drugs Journal, Vol.54, Issue 03: (SCOPUS, ISI Impact factor 0.123) 11. Sabbagh B., Lokesh B. V. S*. and Akowuah G. A., (2017), Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR) Method for the Determination of Dapagliflozin in Tablets; Indian Drugs Journal, Vol.54, Issue 10:52-57 (SCOPUS, ISI Impact factor 0.123) 12. Lokesh BVS*, Prasad YR, Shaik AB. Synthesis and Biological Activity of Novel 2,5- Dichloro-3-Acetylthiophene Chalcone Derivatives. Indian Journal of Pharmaceutical Education and Research. 2017; 51(4S): S679-S690. (SCOPUS, ISI Impact factor:0 248) * Corresponding Author. TEACHING M.Sc., (Pharmaceutical Chemistry) Advanced Pharmaceutical Analysis, Advanced Separation Sciences, Electrochemical Methods of Analysis, PG Research project Undergraduate: Basic Medicinal Chemistry (UCSI Pharmacy program), Pharmaceutical Analysis-I and Pharmaceutical analysis-ii, Medicinal Chemistry components in Gastrointestinal system and Pharmacotherapy, Pulmonary, Renal and Pharmacotherapy, Peripheral Nervous system and Pharmacotherapy, Central Nervous System and Pharmacotherapy, Endocrine System and Pharmacotherapy, Cardiovascular System and Pharmacotherapy 5 P a g e

6 OTHER TEACHING and RESPONSIBILITIES Subjects handled under Curtin University Technology pharmacy program Pharmaceutical Chemistry 200 (School of Pharmacy, Curtin University of Technology, Perth, Australia) MY CURRENT RESEARCH AREA 1) Molecular modification of anticancer agents conjugated with polymers and targeted drug delivery design. 2) Synthesis and biological evolutions of novel heterocyclic compounds from novel chalcones 2) Stability Indicating Assay (SIA) Method development on anticancer drugs, anti-viral drugs and their stability testing studies by HPLC, Advanced spectroscopic techniques like IR, NMR, MS Spectroscopy. 3) Dissolution method development and study of solubility characteristics of poorly watersoluble drugs. 4) Development of nanoparticles as bioactive carriers for treating pulmonary tuberculosis as well as target cancer cell and cell lines 6 P a g e

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