COURSE GUIDE Universidad Católica de Valencia Pharmacology and Toxicology

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1 Pharmacology and Toicology COURSE GUIDE Universidad Católica de Valencia Pharmacology and Toicology THIS SUBJECT IS NOT OFFERED DURING THIS ACADEMIC YEAR

2 Pharmacology and Toicology COURSE GUIDE OF PHARMACOLOGY AND TOXICOLOGY ECTS SUBJECT: Pharmacology and Toicology 6 Field: Pharmacology and Toicology 6 Module: Optional itinerary. Biomedicine 42 Type of Learning: Elective YEAR: Third Semester: First Teacher: Dr. Antonio Pineda Lucena Departament: Applied and Technological sciences antonio.pineda@ucv.es MODULE ORGANIZATION Optional itinerary. Biomedicine 42 ECTS Duration and temporal location within the curriculum: The module is taught in 3º of the degree of Biotechnology. The subject of immunology is taught in the first semester of the third course. Subjects and Courses Subject ECTS Course ECTS Year/ semester Pharmacology and Toicology 6 Pharmacology and Toicology /1 Modeling of Biomolecules Pharmaceutical engineering and Drug Desing 6 6 Modeling of Biomolecules Pharmaceutical engineering and Drug Desing / /1 Drugs 6 Drugs /1 Gene Therapy 6 Gene Therapy /1 Molecular Pathology 6 Molecular Pathology /1

3 Pharmacology and Toicology Clinical Biotechnology 6 Clinical Biotechnology /1 Inmunology 6 Inmunology /1 CURSE GUIDE: PHARMACOLOGY AND TOXICOLOGY Prerequisites: Not established GENERAL GOALS 1. To learn the conceptual foundations and essential principles of the sciences of Pharmacology and Toicology. 2. To acquire basic knowledge of pharmacokinetics and pharmacodynamics. 3. To know the most fundamental technical terminology used in Pharmacology. 4. To know which factors influence the response of the drugs, as well as the correlations between the chemical structure and the pharmacological activity. 5. To know fundamental aspects of the pharmacological action and mechanism of action of the main active principles and groups of drugs. 6. To train the student to epand the knowledge of Pharmacology by himself in the future professional practice. COMPETENCES Competence measuring scale CG01-Capacity to analyze and synthesize CB1-Students acquire and understand knowledge in their field of study based on general secondary education but usually reaching a level that, although supported on advanced tet books, also includes aspects involving state-of-the-art knowledge specific to their area. CB2-Students are able to apply knowledge to their work in a professional way and have the competences enabling them to state and defend views and opinions as well as perform problem-solving tasks in their field of study. CB3-Students are able to collect and interpret relevant data (generally in their field of study) and give opinions that involve reflection on relevant social, scientific or ethical issues.

4 Pharmacology and Toicology CB4-Students can communicate information, ideas, problems and solutions to a specialized or non-specialized audience. CB5-Students develop the necessary learning skills to undertake further studies with a high level of autonomy. CT02-Capacity to organize and plan CT03-Mastering Spanish oral and written communication CT05-Knowing and applying Basic ITC skills related to Biotechnology CT06-Capacity to manage information (capacity to look for and analyze information coming from different types of sources) CT07-Problem solving CT08-Decision making CT09-Capacity to work in interdisciplinary and multidisciplinary team CT10-Interpersonal skills CT11 - Appreciation of diversity and multiculturalism CT12-Critical and self-critical capacity CT13-Ethics CT14-Capacity to learn CT16-Capacity to produce new ideas (creativity) CT15 - Ability to adapt to new situations CT19-Capacity to apply theoretical knowledge CT20-Research skills CT21-Sensitivity to environmental issues CE32-Knowing how to use different specific operating systems and software packages designed for Biotechnology CE33-Knowing and complying with legislation and ethics of biotechnological processes and applications CE34-Knowing main characteristics of Molecular biosciences and biotechnology communication CE30-Solving and analyzing problems posed by biotechnology CE31-Describing and calculating important variables of processes and eperiments CE22-Knowing and understanding contents, principles and theories related to biotechnology

5 Pharmacology and Toicology CE23-Knowing how to use laboratory equipment and to carry out basic operations for each discipline including: safety measures, handling, CE24-Knowing basic and instrument laboratory techniques in the different areas of biotechnology CE25-Knowing how to analyze and understand scientific data related to biotechnology CE27-Knowing and applying action plans and assessment criteria of biotechnology processes CE28-Integrating life science and Engineering into processes of development of biotechnological products and applications CE29-Contrasting and checking results of biotechnological eperimentation LEARNING OUTCOMES R-1 Students have understood and acquired the subject s contents. COMPETENCES CG01, CB1, CB2, CB3, CB4, CB5, CT03, CT06, CT12, CT14, CT19, CT20, CE22, CE25, CE28 R-2 Students are able to solve problems or cases related to those contents by using various resources (literature, computerbased, etc.). R-3 Students are able to work and correctly perform basic activities in a lab in compliance with the relevant safety requirements. They can plan, develop and understand the purpose for the eperience as well as contrast and validate the results obtained. CG01, CB2, CB3 CB4, CT02, CT03, CT05, CT06, CT07, CT12, CT14, CT16, CT19, CT20, CT21, CE25, CE28, CE30, CE31, CE32, CE33 CG01, CB5, CT02, CT05, CT07, CT09, CT10, CT12, CT13, CT14, CT16, CT19, CT20, CT21, CE23, CE24, CE25, CE27, CE28, CE29, CE30, CE32, CE33, CE31 R-4 Students are able to write a clear and well-organized tet on diverse aspects of the subject. CG01, CB1, CB2, CB3, CB4, CB5, CT02, CT03, CT05, CT06, CT09, CT12, CT14, CT16, CT18, CT20, CE25, CE34 R-5 Students are able to adequately present and defend their work. CG01, CB1, CB2, CB3, CB4, CB5, CT02, CT03, CT05, CT06, CT09, CT12, CT14, CT16, CT18, CT20, CE25, CE34 R-6 Students seek bibliographic information from several sources and can analyse it with a critical, constructive attitude. CG01, CB1, CB2, CB3, CB5, CT02, CT05, CT06, CT07, CT12, CT14, CT16, CT18, CT20, CE25, CE31, CE32, CE34

6 Pharmacology and Toicology R-7 Students cooperate with the teacher and peers throughout the learning process. They can work as members of a team. They are respectful, proactive and comply with the subject s organizational rules. CT09, CT10, CT12, CT13, CT15, CT16, CT17, CT18 ON-CAMPUS EDUCATIONAL ACTIVITIES ACTIVITY GROUP WORK Teaching-Learning Methodology Group preparation of readings, essays, problem solving, seminars, papers, reports, etc. to be presented or submitted in theoretical lectures, practical and/or small-group tutoring sessions. Relationship With Learning Outcomes for the subject R-1,R-5,R-6,R- 7,R-9 ECTS 0.73 Work done on the university e- learning platform ( ) INDEPENDENT WORK Student study: Group Individual preparation of readings, essays, problem R-1,R-2,R-3,R-4, R-5,R-6,R-7,R-8,R INDEPENDENT WORK ACTIVITIES ACTIVITY GROUP WORK Teaching-Learning Methodology Group preparation of readings, essays, problem solving, seminars, papers, reports, etc. to be presented or submitted in theoretical lectures, practical and/or small-group tutoring sessions. Relationship With Learning Outcomes for the subject R-1,R-5,R-6,R- 7,R-9 ECTS 0.73 Work done on the university e- learning platform ( ) INDEPENDENT WORK Student study: Group Individual preparation of readings, essays, problem R-1,R-2,R-3,R-4, R-5,R-6,R-7,R-8,R

7 Pharmacology and Toicology SYSTEM FOR ASSESSING THE ACQUISITION OF THE COMPETENCES AND ASSESSMENT SYSTEM* Assessment Tool Allocated Percentage Written test of knowledge a 50% Practical test and report (laboratory) b 12.5% Laboratory Practise Memory 12.5% Ehibition of work 25% * Note: In order to pass the subject the student must obtain at least 5 over 10 points in these assessment tools. MENTION OF DISTINCTION: The mention of Distinction will be awarded to students who have achieved a score equal to or greater than 9.0. The number of Distinctions granted will not eceed 5% of students enrolled in a subject in the corresponding academic year unless enrollment is under 20, in which case only one Distinction may be granted. (Royal Decree 1125/2003). DESCRIPTION OF CONTENTS Introduction to pharmacology. 1,2,3,6,7,20, 23,24,25,29 Pharmacokinetics 1,2,3,6,7,20, 23,24,25,29 Pharmacology of SN Autonomous 1,2,3,6,7,20, 23,24,25,29 Pharmacodynamics 1,2,3,6,7,20,23,24,25,29 Pharmacogenetics and pharmacogenomics 1,2,3,6,7,20, 23,24,25,29 Toicology 1,2,3,6,7,20,23,24,25,29 Laboratory Practice 23,24

8 Pharmacology and Toicology REFERENCES 1. Rang HP., Dale MM., Ritter M., Flower R. Farmacología Elsevier. 2. Flórez, J., Armijo. JA., Mediavilla, A., Farmacología humana Elsevier. 3. Brunton, LL., Lazo, JS., Parker, KL. Goodman & Gilman. Las bases farmacológicas de la terapéutica McGraw-Hill Interamericana. 4. Color Atlas of Pharmacology, Heinz Luellmann (Editor). Thieme Medical Publishers; 3ª edición, Concepts in Clinical Pharmacokinetics, 5th Edition, Joseph T. DiPiro Pharm.D. FCCP Tresguerres,J., Martínez Fernández, V., Navas Serrano, V. Biotecnología aplicada a la medicina Ediciones Díaz de Santos S.A. 7. Principles of Biochemical Toicology, Fourth Edition by John A. Timbrell (Nov 18, 2008)