INTRODUCTION TO NANOMEDICINE AND NANOBIOENGINEERING
|
|
- Linda Phillips
- 5 years ago
- Views:
Transcription
1
2
3 INTRODUCTION TO NANOMEDICINE AND NANOBIOENGINEERING
4 WILEY SERIES IN BIOMEDICAL ENGINEERING AND MULTIDISCIPLINARY INTEGRATED SYSTEMS KAI CHANG, SERIES EDITOR Advances in Optical Imaging for Clinical Medicine Nicusor Iftimia, William R. Brugge, and Daniel X. Hammer (Editors) Antigen Retrieval Immunohistochemistry Based Research and Diagnostics Shan-Rong Shi and Clive R. Taylor Introduction to Nanomedicine and Nanobioengineering Paras N. Prasad
5 INTRODUCTION TO NANOMEDICINE AND NANOBIOENGINEERING PARAS N. PRASAD A JOHN WILEY & SONS, INC., PUBLICATION
6 Copyright 2012 by John Wiley & Sons, Inc. All rights reserved Published by John Wiley & Sons, Inc., Hoboken, New Jersey Published simultaneously in Canada No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, (978) , fax (978) , or on the web at Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) , fax (201) , or online at Limit of Liability/Disclaimer of Warranty: While the publisher and author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages. For general information on our other products and services or for technical support, please contact our Customer Care Department within the United States at (800) , outside the United States at (317) or fax (317) Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic formats. For more information about Wiley products, visit our web site at Library of Congress Cataloging-in-Publication Data: Prasad, Paras N. Introduction to nanomedicine and nanobioengineering / Paras N. Prasad. p. ; cm. Transforming healthcare with nanotechnology Includes bibliographical references. ISBN I. Title. II. Title: Transforming healthcare with nanotechnology. [DNLM: 1. Nanomedicine methods. QT 36.5] '4 dc Printed in the United States of America
7 CONTENTS PREFACE ACKNOWLEDGMENTS xiii xv 1 INTRODUCTION Nanomedicine: A Global Vision / The Nanotechnology Revolution: Realization of Asimov s Fiction / Nanomedicine: A New Era in Personalized Medicine / Nanomedicine: A Promise or Reality? / A New Frontier: Multidisciplinary Challenges and Opportunities / Scope of the Book: Multidisciplinary Education, Training, and Research / 12 References / 13 2 THE HUMAN BODY Introductory Concepts / Cellular Structure / Various Types of Cells / Biochemical Makeup of Cells / Other Important Cellular Components / Cellular Processes / 30 v
8 vi Contents 2.7. Organization of Cells into Tissues / Types of Tissues and Their Functions / Various Organs and Organ Systems in the Body / Tumors and Cancers / 45 Highlights of the Chapter / 46 Exercises / 48 References / 49 3 NANOCARRIERS Nanocarriers: Delivering Payloads to Needed Sites / The Various Nanoformulations for Nanomedicine / Viruses as Nanocarriers / Polymeric Nanocarriers / Lipid-Based Nanocarriers / Dendrimers / Carbon Nanostructures / Inorganic Nanoparticles / PEBBLE / Nanoclinics / Nanoplexes / New-Generation Nanocarriers / 69 Highlights of the Chapter / 70 Exercises / 72 References / 73 4 NANOCHEMISTRY OF NANOCARRIERS Nanochemistry and Nanomedicine / Top-Down Approaches / Mechanical Milling / Dip-Pen Nanolithography / PRINT Process / Laser Ablation / Bottom-Up Approaches / Dendrimers / Microemulsion Chemistry / Hot-Colloidal Synthesis / Seed-Mediated Synthesis of Anisotropic Metallic Nanostructures / Reprecipitation Method / 90
9 Contents vii 4.4. Combination of Bottom-Up and Top-Down Approaches / Nanoparticle Surface Modification / Functionalization and Bioconjugation / 95 Highlights of the Chapter / 97 Exercises / 99 References / MULTIFUNCTIONALITIES FOR DIAGNOSTICS AND THERAPY The Various Functionalities / Optical Functionalities / Optical Nanoprobes / Magnetic Functionality / Thermal Functionality / Radioactive Functionality / Biological Functionality / Multifunctionality / 125 Highlights of the Chapter / 128 Exercises / 130 References / CROSSING THE BIOLOGICAL BARRIERS Various Delivery Pathways / Various Biological Barriers / Stealth Nanoparticles / The Various In Vitro Barrier Models / 141 Highlights of the Chapter / 144 Exercises / 145 References / BIOTARGETING Biotargeting: Why We Need It / Targeted Biological Sites / Intracellular Uptake / Targeting Strategies / Targeting Groups / 155 Highlights of the Chapter / 159 Exercises / 160 References / 161
10 viii Contents 8 MULTIMODAL BIOMEDICAL IMAGING Biomedical Imaging Techniques / Optical Bioimaging / Fluorescence Microscopy / Quantitative FRET Microscopy / Technical Challenges for In Vitro Imaging / In Vivo Optical Imaging / Optical Coherence Tomography / Super-Resolution Fluorescence Microscopy / Magnetic Resonance Imaging / X-Ray CT Imaging / Radio Imaging / Ultrasound Imaging / Photoacoustic Imaging / Multimodal Imaging / 192 Highlights of the Chapter / 193 Exercises / 200 References / BIOSENSING Principles of Biosensing / Optical Biosensors / Fluorescencs Sensors / Plasmonic Sensors / Photonic Crystal Sensors / Magnetic Biosensors / Electrical Biosensing / Electrochemical Biosensing / Electrochemiluminescence Biosensing / In Vivo Bioelectronic Sensors / 239 Highlights of the Chapter / 241 Exercises / 245 References / HIGH-THROUGHPUT MULTIPLEXED DIAGNOSTICS Comprehensive Diagnostic Strategy / Flow Cytometry / Enzyme-Linked Immunosorbent Assay (ELISA) / 264
11 Contents ix Microarrays Technology / Suspension Bead Assay / 277 Highlights of the Chapter / 281 Exercises / 285 References / NANOPHARMACOTHERAPY Nanopharmacotherapy: An Overview / Modes of Nanoformulation for Nanopharmacotherapy / Pharmacokinetics / Biodistribution / Pharmacodynamics / Controlled Release by External Activation / 299 Highlights of the Chapter / 300 Exercises / 302 References / THE HUMAN CIRCULATORY SYSTEM AND THERANOSTICS Blood Fluidics and Cardiovascular System / Circulatory-System-Based Disease Profiling / Methods to Monitor Blood Flow / Therapeutic Approaches Utilizing Manipulation of Blood Flow / Lymph Node Mapping / Lymphatic Drug Delivery / 322 Highlights of the Chapter / 322 Exercises / 326 References / NANOTECHNOLOGY FOR CANCER Benefits of Cancer Nanotechnology / Chemotherapy / Cancer Gene Therapy / Photodynamic Therapy / Magnetic Therapy / Photothermal Therapy / Neutron Capture Therapy / 357
12 x Contents Circulating Tumor Cells / NCI Alliance for Cancer Nanotechnology / 360 Highlights of the Chapter / 360 Exercises / 362 References / GENE THERAPY The Principles, Steps, and Impact of Gene Therapy / Methods of Gene Delivery / Gene Augmentation Therapy / Gene Silencing Therapy / Indirect Gene Therapy Modulating Innate Immune Response / Transmucosal Gene Delivery / 385 Highlights of the Chapter / 386 Exercises / 388 References / NANOTECHNOLOGY FOR INFECTIOUS DISEASES Pathogen Infections and Nanoparticle-Based Approaches / HIV / Diagnosis / Vaccines and Antimicrobial Drugs / Therapy / Influenza / Diagnosis / Vaccines / Therapy / Tuberculosis / Diagnosis / TB Vaccine / Therapy / Malaria / Vaccines / Therapy / 420 Highlights of the Chapter / 422 Exercises / 424 References / 426
13 Contents xi 16 REJUVENATION THERAPY Rejuvenation Therapy: Fantasy or Reality? / Free Radical Scavenging / Chelation Therapy / Hormone Therapy / 441 Highlights of the Chapter / 442 Exercises / 443 References / STEM CELL BIOTECHNOLOGY Stem Cell Biotechnology: Overview / Cell Reprogramming / Gene Transfection / Somatic Cell Transdifferentiation / Stem Cell Sorting / Stem Cell Tracking / 454 Highlights of the Chapter / 456 Exercises / 456 References / TISSUE ENGINEERING Tissue Engineering: Overview / Tissue Regeneration / Nanotechnology in Tissue Engineering / Nanofibers for Tissue Engineering / Nanoparticle Delivery of Biomolecules / Magnetically Assisted Tissue Engineering / Tissue/Organ Printing / Tissue Bonding / 477 Highlights of the Chapter / 479 Exercises / 482 References / NANODERMATOLOGY AND NANOCOSMETICS Delivery Through Skin / Skin Care and Nanotechnology / Various Nanoparticles for Dermatology and Cosmetics / Nanodermatology / 492
14 xii Contents Nanocosmetics / Nanotoxicology of the Skin / 497 Highlights of the Chapter / 497 Exercises / 498 References / NANODENTISTRY Nanotechnology for Dental Care / Nanoparticles for Preventive Dentistry / Nanomaterials for Restorative Dentistry / Regenerative Dentistry / Nanoparticle-Enhanced Dental Imaging and Oral Diagnostics / Nanorobotics for Dentistry / 522 Highlights of the Chapter / 522 Exercises / 524 References / NANOTOXICITY Toxicity of Nanoparticles / Cytotoxicity / In Vitro Cytotoxicity Assays / In Vivo Toxicity / In Vivo Toxicity Evaluation / Nanotoxicity Studies on Selected Nanoparticles / 542 Highlights of the Chapter / 547 Exercises / 550 References / 551 INDEX 555
15 PREFACE Nanomedicine and nanobioengineering, defined respectively by the fusion of nanotechnology with medicine and bioengineering, are emerging new frontiers, providing challenges for fundamental research and opportunities for new biotechnologies. These fields promise to make a major impact on healthcare worldwide. They are multidisciplinary fields, creating opportunities in physics, chemistry, applied sciences, engineering, and biology, as well as in biomedical technology and drug development. A good number of books and reviews discuss selective aspects of nanomedicine and nanobioengineering. However, there is a need for a comprehensive monograph that provides a unified synthesis of these two fields and their joint impact on global healthcare. This book fills this need, by providing an integrated description of nanomedicine and nanobioengineering for new-generation diagnostics and therapy. The comprehensive, multidisciplinary program at our Institute in this integrated field of nanomedicine received early, generous funding from the John R. Oishei Foundation in Buffalo, New York; and the resulting work provided the inspiration and much of the impetus to undertake this writing. The objective of this book is to provide a basic knowledge of a broad range of topics in an integrated manner so that individuals in all disciplines can rapidly acquire the minimal necessary background for research and development in this field. The author intends this monograph to serve both as a textbook for education and training and as a reference book that aids research and development in areas integrating nanotechnology with medicine and bioengineering. Another aim of the book is to stimulate the interest of researchers, industries, and businesses, as well as to foster collaboration xiii
INTERNATIONAL PROJECT MANAGEMENT:
INTERNATIONAL PROJECT MANAGEMENT: LEADERSHIP IN COMPLEX ENVIRONMENTS International Project Management: Leadership in Complex Environments Copyright 2010 John Wiley & Sons, Inc. ISBN: 978-0-470-57882-7
More informationt e g y s t r a i m p l e m e n t a t i o n M E N TA L L A N G U A G M O D E L S S T O R Y M A P S S O C I A L M E D I A
D E S I G N V I S U A L T H I N K I N G L A N G U A G V I R T U A L W O R K S O C I A L M E D I A s t r a M E E T t e g y V I S U A L I N G S R T U P S C O L L A B O R AT I O N S T O R Y M A P S M O D
More informationMANAGEMENT OF TECHNOLOGY
MANAGEMENT OF TECHNOLOGY MANAGEMENT OF TECHNOLOGY Managing Effectively in Technology-Intensive Organizations Hans J. Thamhain This book is printed on acid-free paper. Copyright 2005 by John Wiley & Sons,
More informationThe Procurement and Supply Manager s Desk Reference
The Procurement and Supply Manager s Desk Reference The Procurement and Supply Manager s Desk Reference Second Edition FRED SOLLISH, MS JOHN SEMANIK, MBA John Wiley & Sons, Inc. Copyright 2012 by John
More informationINTRODUCTION TO NANOMEDICINE AND NANOBIOENGINEERING
INTRODUCTION TO NANOMEDICINE AND NANOBIOENGINEERING WILEY SERIES IN BIOMEDICAL ENGINEERING AND MULTIDISCIPLINARY INTEGRATED SYSTEMS KAI CHANG, SERIES EDITOR Advances in Optical Imaging for Clinical Medicine
More informationTroubleshooting the Sequencing Batch Reactor
Troubleshooting the Sequencing Batch Reactor Illustrations by Brittany Lytle A John Wiley & Sons, Inc., Publication Troubleshooting the Sequencing Batch Reactor WASTEWATER MICROBIOLOGY SERIES Editor Nitrification
More informationForensic Accounting and Fraud Investigation for Non-Experts
Forensic Accounting and Fraud Investigation for Non-Experts Forensic Accounting and Fraud Investigation for Non-Experts Third Edition HOWARD SILVERSTONE MICHAEL SHEETZ STEPHEN PEDNEAULT FRANK RUDEWICZ
More informationDiagnosing and Changing Organizational Culture
Diagnosing and Changing Organizational Culture To download PDFs of the OCAI (Organizational Culture Assessment Instrument) and the MSAI (Management Skills Assessment Instrument) please go to www.josseybass.com/go/cameron.
More informationLIFE CYCLE RELIABILITY ENGINEERING
LIFE CYCLE RELIABILITY ENGINEERING Life Cycle Reliability Engineering. Guangbin Yang Copyright 2007 John Wiley &Sons, Inc. ISBN: 978-0-471-71529-0 LIFE CYCLE RELIABILITY ENGINEERING Guangbin Yang Ford
More informationManaging Exports Navigating the Complex Rules, Controls, Barriers, and Laws Frank Reynolds
Managing Exports Navigating the Complex Rules, Controls, Barriers, and Laws Frank Reynolds JOHN WILEY & SONS, INC. Managing Exports Managing Exports Navigating the Complex Rules, Controls, Barriers,
More informationOPERATIONAL REVIEW WORKBOOK Case Studies, Forms, and Exercises Rob Reider John Wiley & Sons, Inc. New York Chichester Weinheim Brisbane Toronto Singap
OPERATIONAL REVIEW WORKBOOK Case Studies, Forms, and Exercises Rob Reider John Wiley & Sons, Inc. New York Chichester Weinheim Brisbane Toronto Singapore OPERATIONAL REVIEW WORKBOOK OPERATIONAL REVIEW
More informationSarbanes-Oxley Internal Controls
Sarbanes-Oxley Internal Controls Effective Auditing with AS5, CobiT, and ITIL ROBERT R. MOELLER John Wiley & Sons, Inc. Sarbanes-Oxley Internal Controls Sarbanes-Oxley Internal Controls Effective Auditing
More informationCommonsense Talent Management
Commonsense Talent Management Commonsense Talent Management USING STRATEGIC HUMAN RESOURCES TO IMPROVE COMPANY PERFORMANCE Steven T. Hunt Copyright 2014 by John Wiley & Sons, Inc. All rights reserved.
More informationSTRATEGIC MARKETING FOR HEALTH CARE ORGANIZATIONS
STRATEGIC MARKETING FOR HEALTH CARE ORGANIZATIONS Building a Customer-Driven Health System PHILIP KOTLER, JOEL SHALOWITZ, AND ROBERT J. STEVENS STRATEGIC MARKETING FOR HEALTH CARE ORGANIZATIONS STRATEGIC
More informationCORPORATE FINANCE WORKBOOK
CORPORATE FINANCE WORKBOOK CFA Institute is the premier association for investment professionals around the world, with over 101,000 members in 134 countries. Since 1963 the organization has developed
More informationBEST PRACTICES IN PLANNING AND PERFORMANCE MANAGEMENT RADICALLY RETHINKING MANAGEMENT FOR A VOLATILE WORLD. Third Edition. David A. J.
BEST PRACTICES IN PLANNING AND PERFORMANCE MANAGEMENT RADICALLY RETHINKING MANAGEMENT FOR A VOLATILE WORLD Third Edition David A. J. Axson Best Practices in Planning and Performance Management Best Practices
More informationCivil Engineer s Handbook of Professional Practice
Civil Engineer s Handbook of Professional Practice Civil Engineer s Handbook of Professional Practice Karen Lee Hansen and Kent E. Zenobia John Wiley & Sons, Inc. This book is printed on acid-free paper.
More informationHow to Estimate with. RSMeans Data
How to Estimate with RSMeans Data How to Estimate with RSMeans Data Basic Skills for Building Construction Fourth Edition RSMeans and Saleh A. Mubarak, Ph.D. Barbara Balboni, Technical Editor RSMeans
More informationFor more information on any of the above titles, please visit
ESSENTIALS of XBRL Financial Reporting in the 21st Century Bryan Bergeron John Wiley & Sons, Inc. ESSENTIALS of XBRL Essentials Series The Essentials Series was created for busy business advisory and
More informationMANAGEMENT ACCOUNTING BEST PRACTICES
MANAGEMENT ACCOUNTING BEST PRACTICES A Guide for the Professional Accountant STEVEN M. BRAGG John Wiley & Sons, Inc. Management Accounting Best Practices A Guide for the Professional Accountant MANAGEMENT
More informationSTRUCTURAL STABILITY OF STEEL: CONCEPTS AND APPLICATIONS FOR STRUCTURAL ENGINEERS
STRUCTURAL STABILITY OF STEEL: CONCEPTS AND APPLICATIONS FOR STRUCTURAL ENGINEERS Structural Stability of Steel: Concepts and Applications for Structural Engineers Theodore V. Galambos Andrea E. Surovek
More informationAccounts Payable Best Practices Mary S. Schaeffer Executive Editor IOMA s Report on Managing Accounts Payable Co-creator The Accounts Payable Certification Programs John Wiley & Sons, Inc. Accounts Payable
More informationThe Executive Director s GUIDE
JOSSEY-BASS NONPROFIT GUIDEBOOK S E R I E S The Executive Director s GUIDE TO THRIVING AS A NONPROFIT LEADER SECOND EDITION SECOND EDITION MIM CARLSON MARGARET DONOHOE The Executive Director s Guide to
More informationSarbanes-Oxley and the New Internal Auditing Rules
Sarbanes-Oxley and the New Internal Auditing Rules ROBERT R. MOELLER John Wiley & Sons, Inc. Sarbanes-Oxley and the New Internal Auditing Rules Sarbanes-Oxley and the New Internal Auditing Rules ROBERT
More informationmarketing 3.0 PHILIP KOTLER From Products to Customers to the Human Spirit JOHN WILEY & SONS, INC.
marketing 3.0 marketing 3.0 From Products to Customers to the Human Spirit PHILIP KOTLER HERMAWAN KARTAJAYA IWAN SETIAWAN JOHN WILEY & SONS, INC. Copyright C by 2010 by Philip Kotler, Hermawan Kartajaya,
More informationBridge Design and Evaluation
Bridge Design and Evaluation Bridge Design and Evaluation LRFD and LRFR Gongkang Fu John Wiley & Sons, Inc. Cover Design: Michael Rutkowski Cover Photograph: Courtesy of Alamy Creativity/Alamy This book
More informationSarbanes-Oxley. Guide for Finance and Information Technology Professionals SANJAY ANAND. John Wiley & Sons, Inc.
Sarbanes-Oxley Guide for Finance and Information Technology Professionals SANJAY ANAND John Wiley & Sons, Inc. Sarbanes-Oxley Guide for Finance and Information Technology Professionals Sarbanes-Oxley
More informationCredit Risk Scorecards
Credit Risk Scorecards Developing and Implementing Intelligent Credit Scoring Naeem Siddiqi John Wiley & Sons, Inc. Additional praise for Credit Risk Scorecards... An essential book for anyone interested
More informationGETTING STARTED IN PERSONAL AND EXECUTIVE COACHING
GETTING STARTED IN PERSONAL AND EXECUTIVE COACHING How to Create a Thriving Coaching Practice Stephen G. Fairley Chris E. Stout John Wiley & Sons, Inc. GETTING STARTED IN PERSONAL AND EXECUTIVE COACHING
More informationExecutive Compensation Best Practices
Executive Compensation Best Practices Frederick D. Lipman Steven E. Hall John Wiley & Sons, Inc. Executive Compensation Best Practices Executive Compensation Best Practices Frederick D. Lipman Steven
More informationBusiness Intelligence Competency Centers A Team Approach to Maximizing Competitive Advantage
Business Intelligence Competency Centers A Team Approach to Maximizing Competitive Advantage Gloria J. Miller Dagmar Bräutigam Stefanie V. Gerlach John Wiley & Sons, Inc. Business Intelligence Competency
More informationAbout This Book. Why is this topic important? What can you achieve with this book? How is this book organized?
About This Book Why is this topic important? Trainers sometimes fail to ask enough questions or the right question prior to designing, redesigning, or presenting a training program as the solution to a
More informationScrivener Publishing 100 Cummings Center, Suite 541J Beverly, MA
Biofuels Production Scrivener Publishing 100 Cummings Center, Suite 541J Beverly, MA 01915-6106 Publishers at Scrivener Martin Scrivener (martin@scrivenerpublishing.com) Phillip Carmical (pcarmical@scrivenerpublishing.com)
More informationJOHN BASCHAB JON PIOT
T H E PROFESSIONAL SERVICES FIRM BIBLE JOHN BASCHAB JON PIOT John Wiley & Sons, Inc. T H E PROFESSIONAL SERVICES FIRM BIBLE T H E PROFESSIONAL SERVICES FIRM BIBLE JOHN BASCHAB JON PIOT John Wiley & Sons,
More informationCOUPLED BIOLUMINESCENT ASSAYS
COUPLED BIOLUMINESCENT ASSAYS Methods, Evaluations, and Applications MICHAEL J. COREY A John Wiley & Sons, Inc., Publication COUPLED BIOLUMINESCENT ASSAYS COUPLED BIOLUMINESCENT ASSAYS Methods, Evaluations,
More informationFrequently Asked Questions
K O U Z E S P O S N E R THE LEADERSHIP CHALLE NGE VALUES CARDS Frequently Asked Questions JAMES M. KOUZES AND BARRY Z. POSNER, WITH JO BELL AND RENEE HARNESS i Copyright 2010 by James M. Kouzes & Barry
More informationWELDING METALLURGY SECOND EDITION Sindo Kou Professor and Chair Department of Materials Science and Engineering University of Wisconsin A JOHN WILEY & SONS, INC., PUBLICATION WELDING METALLURGY SECOND
More informationJOHN WILEY & SONS, INC.
Consultation Skills for Mental Health Professionals Richard W. Sears John R. Rudisill Carrie Mason-Sears JOHN WILEY & SONS, INC. Consultation Skills for Mental Health Professionals Consultation Skills
More informationWELDING METALLURGY AND WELDABILITY OF NICKEL-BASE ALLOYS
WELDING METALLURGY AND WELDABILITY OF NICKEL-BASE ALLOYS John N. DuPont John C. Lippold Samuel D. Kiser A JOHN WILEY & SONS, INC., PUBLICATION WELDING METALLURGY AND WELDABILITY OF NICKEL-BASE ALLOYS
More informationINTEGRATION OF ALTERNATIVE SOURCES OF ENERGY
INTEGRATION OF ALTERNATIVE SOURCES OF ENERGY FELIX A. FARRET M. GODOY SIMÕES A JOHN WILEY & SONS, INC., PUBLICATION INTEGRATION OF ALTERNATIVE SOURCES OF ENERGY INTEGRATION OF ALTERNATIVE SOURCES OF
More informationJohn Wiley & Sons, Inc.
Corporate Fraud Case Studies in Detection and Prevention JOHN D. O GARA John Wiley & Sons, Inc. Corporate Fraud Corporate Fraud Case Studies in Detection and Prevention JOHN D. O GARA John Wiley & Sons,
More informationENTERPRISE PERFORMANCE MANAGEMENT DONE RIGHT
ENTERPRISE PERFORMANCE MANAGEMENT DONE RIGHT ENTERPRISE PERFORMANCE MANAGEMENT DONE RIGHT AN OPERATING SYSTEM FOR YOUR ORGANIZATION Ron Dimon Copyright 2013 by John Wiley & Sons, Inc. All rights reserved.
More informationA Guide to Creating a Successful Algorithmic Trading Strategy
A Guide to Creating a Successful Algorithmic Trading Strategy The Wiley Trading series features books by traders who have survived the market s ever changing temperament and have prospered some by reinventing
More informationSOFTWARE EVOLUTION AND MAINTENANCE
SOFTWARE EVOLUTION AND MAINTENANCE A PRACTITIONER S APPROACH PRIYADARSHI TRIPATHY KSHIRASAGAR NAIK SOFTWARE EVOLUTION AND MAINTENANCE SOFTWARE EVOLUTION AND MAINTENANCE A Practitioner s Approach PRIYADARSHI
More informationECONOMICS FOR INVESTMENT DECISION MAKERS WORKBOOK
ECONOMICS FOR INVESTMENT DECISION MAKERS WORKBOOK CFA Institute is the premier association for investment professionals around the world, with over 117,000 members in 134 countries. Since 1963 the organization
More informationGovernance, Risk Management, and Compliance
Additional praise for Governance, Risk Management, and Compliance It Can t Happen to Us Avoiding Corporate Disaster While Driving Success In this complex and perilous global marketplace, it is vital that
More informationThe. Rational. Project Manager A THINKING TEAM S GUIDE TO GETTING WORK DONE. Andrew Longman Jim Mullins KEPNER-TREGOE, INC. John Wiley & Sons, Inc.
The Rational Project Manager A THINKING TEAM S GUIDE TO GETTING WORK DONE Andrew Longman Jim Mullins KEPNER-TREGOE, INC. John Wiley & Sons, Inc. The Rational Project Manager The Rational Project Manager
More informationDESIGN OF WATER SUPPLY PIPE NETWORKS
DESIGN OF WATER SUPPLY PIPE NETWORKS DESIGN OF WATER SUPPLY PIPE NETWORKS Prabhata K. Swamee Ashok K. Sharma Copyright # 2008 by John Wiley & Sons, Inc. All rights reserved Published by John Wiley & Sons,
More informationLeadership for the Common Good
Leadership for the Common Good Tackling Public Problems in a Shared-Power World Second Edition Barbara C. Crosby John M. Bryson Leadership for the Common Good Leadership for the Common Good Tackling
More informationCOMPLYING WITH. SECTION 404 A Guide for Small Publicly Held Companies SARBANES- OXLEY LYNFORD GRAHAM
COMPLYING WITH SARBANES- OXLEY SECTION 404 A Guide for Small Publicly Held Companies LYNFORD GRAHAM Complying with Sarbanes-Oxley Section 404 Complying with Sarbanes-Oxley Section 404 A Guide for Small
More informationMANAGING AND LEADING SOFTWARE PROJECTS RICHARD E. (DICK) FAIRLEY A JOHN WILEY & SONS, INC., PUBLICATION
MANAGING AND LEADING SOFTWARE PROJECTS RICHARD E. (DICK) FAIRLEY A JOHN WILEY & SONS, INC., PUBLICATION MANAGING AND LEADING SOFTWARE PROJECTS Press Operating Committee Chair Linda Shafer former Director,
More informationSTAGING TO SELL THE SECRET TO SELLING HOMES IN A DOWN MARKET BARB SCHWARZ SOLD SOLD SOLD THE INVENTOR OF HOME STAGING
STAGING TO SELL THE SECRET TO SELLING HOMES IN A DOWN MARKET SOLD SOLD SOLD BARB SCHWARZ THE INVENTOR OF HOME STAGING STAGING TO SELL STAGING TO SELL The Secret to Selling Homes in a Down Market BARB
More informationDRUG SAFETY EVALUATION
DRUG SAFETY EVALUATION DRUG SAFETY EVALUATION SHAYNE C. GAD A John Wiley & Sons, Inc., Publication This book is printed on acid-free paper. Copyright # 2002 by John Wiley and Sons, Inc., New York. All
More informationBIOMEDICAL ENGINEERING ACADEMIC PRESS SERIES IN BIOMEDICAL ENGINEERING ELSEVIER ACADEMIC PRESS. "mmmmmm
ACADEMIC PRESS SERIES IN BIOMEDICAL ENGINEERING ELSEVIER ACADEMIC PRESS "mmmmmm vmnkmmwmmm'''mmmmmmmmmimmmmmmmmiinivmiv INTRODUCTION TO BIOMEDICAL ENGINEERING SECOND EDITION JOHN SUSAN foseph END ERIE
More informationEDGAR H. SCHEIN A N D R E V I S E D E D I T I O N N E W
EDGAR H. SCHEIN THE CORPORATE CULTURE SURVIVAL GUIDE A N D R E V I S E D E D I T I O N N E W The Corporate Culture Survival Guide Join Us at Josseybass.com Register at www.josseybass.com/email for more
More informationOrganizational Consulting How to Be an Effective Internal Change Agent
Organizational Consulting How to Be an Effective Internal Change Agent Alan Weiss, PhD John Wiley & Sons, Inc. Organizational Consulting Also by Alan Weiss THE ULTIMATE CONSULTANT SERIES Life Balance:
More informationStreetsmart Financial Basics for Nonprofit Managers
Streetsmart Financial Basics for Nonprofit Managers Third Edition Thomas A. McLaughlin John Wiley & Sons, Inc. Streetsmart Financial Basics for Nonprofit Managers Streetsmart Financial Basics for Nonprofit
More informationHow to Be an Investment Banker
How to Be an Investment Banker Founded in 1807, John Wiley & Sons is the oldest independent publishing company in the United States. With offices in North America, Europe, Australia and Asia, Wiley is
More informationEFFECTIVE INTERPERSONAL AND TEAM COMMUNICATION SKILLS FOR ENGINEERS
EFFECTIVE INTERPERSONAL AND TEAM COMMUNICATION SKILLS FOR ENGINEERS IEEE Press 445 Hoes Lane Piscataway, NJ 08854 IEEE Press Editorial Board 2012 John Anderson, Editor in Chief Ramesh Abhari George W.
More informationNANOTHERAPEUTICS. Drug Delivery Concepts in Nanoscience
NANOTHERAPEUTICS Drug Delivery Concepts in Nanoscience This page intentionally left blank NANOTHERAPEUTICS Drug Delivery Concepts in Nanoscience edited by Alf Lamprecht of France PAN STANFORD PUBLISHING
More informationProject Management. Budgeting, Tracking, and Repor ting. Costs and Prof itability second edition
Praise for Project Management Accounting Project Management in relation to a company s mission, objectives, and strategy Project Management in an agile business Coverage of agile Project Management as
More informationDATA MINING AND BUSINESS ANALYTICS WITH R
DATA MINING AND BUSINESS ANALYTICS WITH R DATA MINING AND BUSINESS ANALYTICS WITH R Johannes Ledolter Department of Management Sciences Tippie College of Business University of Iowa Iowa City, Iowa Copyright
More informationEnterprise Risk Management
Enterprise Risk Management A Methodology for Achieving Strategic Objectives Gregory Monahan John Wiley & Sons, Inc. Enterprise Risk Management Enterprise Risk Management A Methodology for Achieving Strategic
More informationFUNDAMENTALS OF SEMICONDUCTOR MANUFACTURING AND PROCESS CONTROL
FUNDAMENTALS OF SEMICONDUCTOR MANUFACTURING AND PROCESS CONTROL FUNDAMENTALS OF SEMICONDUCTOR MANUFACTURING AND PROCESS CONTROL Gary S. May, Ph.D. Georgia Institute of Technology Atlanta, Georgia Costas
More informationThe Competitive Advantage
Business Process outsourcing The Competitive Advantage RICK L. CLICK THOMAS N. DUENING John Wiley & Sons, Inc. Business Process outsourcing Business Process outsourcing The Competitive Advantage RICK
More informationFraud and Fraud Detection
Fraud and Fraud Detection The Wiley Corporate F&A series provides information, tools, and insights to corporate professionals responsible for issues affecting the profitability of their company, from accounting
More informationEnterprise Risk Management
Enterprise Risk Management Join Us at Josseybass.como Register at www.josseybass.com/email for more information on our publications, authors, and to receive special offers. Enterprise Risk Management A
More informatione m ot i o n a l i n t e l l i g e n c e skills assessment EISA Fr e q u e n t l y Steven J. Stein Derek Mann Peter Papadogiannis Wendy Gordon
e m ot i o n a l i n t e l l i g e n c e skills assessment EISA sa gence M e nt» Fr e q u e n t l y Asked Questions Steven J. Stein Derek Mann Peter Papadogiannis Wendy Gordon Copyright 2010 by Multi-Health
More informationFlow Cytometry. Principles and Applications. Edited by. Marion G. Macey, PhD
Flow Cytometry Flow Cytometry Principles and Applications Edited by Marion G. Macey, PhD Department of Haematology The Royal London Hospital London, United Kingdom 2007 Humana Press Inc. 999 Riverview
More informationVeterinarian s Guide to Maximizing Biopsy Results
Veterinarian s Guide to Maximizing Biopsy Results Veterinarian s Guide to Maximizing Biopsy Results F. Yvonne Schulman DVM, Diplomate ACVP This edition first published 2016 2016 John Wiley & Sons, Inc.
More informationCOURSE OUTLINE. Biology 112 Microbiology
Degree Applicable Glendale Community College October, 2013 COURSE OUTLINE Biology 112 Microbiology I. Catalog Statement Biology 112 is a study of microorganisms (algae, bacteria, fungi, protozoa, and viruses).
More informationPan Stanford Series on Biomedical Nanotechnology
Pan Stanford Series on Biomedical Nanotechnology Series Editors Vladimir Torchilin and Mansoor Amiji Titles in the Series Vol. 1 Handbook of Materials for Nanomedicine Vladimir Torchilin and Mansoor Amiji,
More informationSUPPLY CHAIN MANAGEMENT. Best Practices. Second Edition. David Blanchard
SUPPLY CHAIN MANAGEMENT Best Practices Second Edition David Blanchard Supply Chain Management Best Practices Supply Chain Management Best Practices Second Edition DAVID BLANCHARD John Wiley & Sons, Inc.
More informationORGANIZATIONAL PSYCHOLOGY
ORGANIZATIONAL PSYCHOLOGY ORGANIZATIONAL PSYCHOLOGY A SCIENTIST-PRACTITIONER APPROACH Third Edition Steve M. Jex and Thomas W. Britt Cover image: istock.com/tntemerson Cover design: Wiley This book is
More informationWhat Works ffirs 12 July 2012; 10:12:55
What Works What Works Robert Cornish Wil Seabrook John Wiley & Sons, Inc. Copyright 2012 by Robert Cornish. All rights reserved. Published by John Wiley & Sons, Inc., Hoboken, New Jersey. Published simultaneously
More informationMicrobiology An Introduction Tortora Funke Case Eleventh Edition
Microbiology An Introduction Tortora Funke Case Eleventh Edition Pearson Education Limited Edinburgh Gate Harlow Essex CM20 2JE England and Associated Companies throughout the world Visit us on the World
More informationBioNanoMed March, Krems/Austria
26-28 March, Krems/Austria TOPICS Nanotechnology Enables Personalized Medicine New Frontiers in Medicine & Biology A - Novel Nanomedical Solutions - Advances in Nanomedicine Neurodegenerative Diseases,
More informationBioNanoMed March, Krems/Austria
13-15 March, Krems/Austria TOPICS Nanotechnology Enables Personalized Medicine New Frontiers in Medicine & Biology - Novel Nanomedical Solutions - Advances in Nanomedicine Cancer / Oncology, Neurodegenerative
More informationS TRUCTURAL W OOD D ESIGN
S TRUCTURAL W OOD D ESIGN Structural Wood Design: A Practice-Oriented Approach Using the ASD Method. Abi Aghayere and Jason Vigil Copyright 2007 John Wiley & Sons, Inc. S TRUCTURAL W OOD D ESIGN A PRACTICE-ORIENTED
More informationPHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELING AND SIMULATIONS
PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELING AND SIMULATIONS PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODELING AND SIMULATIONS Principles, Methods, and Applications in the Pharmaceutical Industry
More informationKEN SCHWABER and JEFF SUTHERLAND
KEN SCHWABER and JEFF SUTHERLAND John Wiley & Sons, Inc. Copyright # 2012 by Ken Schwaber and Jeff Sutherland. All rights reserved. Published by John Wiley & Sons, Inc., Hoboken, New Jersey. Published
More informationService-Oriented Architecture
Executive s Guide to Service-Oriented Architecture ERIC A. MARKS MICHAEL BELL John Wiley & Sons, Inc. Executive s Guide to Service-Oriented Architecture ERIC A. MARKS MICHAEL BELL John Wiley & Sons, Inc.
More informationMolecular Diagnostics
Molecular Diagnostics Part II: Regulations, Markets & Companies By Prof. K. K. Jain MD, FRACS, FFPM Jain PharmaBiotech Basel, Switzerland May 2018 A Jain PharmaBiotech Report A U T H O R ' S B I O G R
More informationPHARMACEUTICAL APPLICATIONS OF RAMAN SPECTROSCOPY
PHARMACEUTICAL APPLICATIONS OF RAMAN SPECTROSCOPY PHARMACEUTICAL APPLICATIONS OF RAMAN SPECTROSCOPY Edited By SLOBODAN ŠAŠIĆ Pfizer, Ltd., Sandwich, UK WILEY-INTERSCIENCE A JOHN WILEY & SONS, INC., PUBLICATION
More informationBiomedical Data Science
510.311 Structure of Materials 510.312 Thermodynamics/Materials 510.313 Mechanical Properties of Materials 510.314 Electronic Properties of Materials 510.315 Physical Chemistry of Materials II 510.316
More informationEnvironmentally Conscious Materials Handling
Environmentally Conscious Materials Handling Environmentally Conscious Materials Handling Edited by Myer Kutz 2009 John Wiley & Sons, Inc. ISBN: 978-0-470-17070-0 Environmentally Conscious Materials Handling
More informationCancer Nanotechnology and Nanotoxicology: Response to NIH RFAs
Cancer Nanotechnology and Nanotoxicology: Response to NIH RFAs Oct 13, 2015 nanoutah 2015 M.M. Janát-Amsbury, MD, PhD and H. Ghandehari, PhD Obstetrics and Gynecology/Gynecologic Oncology Pharmaceutics
More informationTHROUGHPUT ACCOUNTING
THROUGHPUT ACCOUNTING A GUIDE TO CONSTRAINT MANAGEMENT STEVEN M. BRAGG JOHN WILEY &SONS, INC. THROUGHPUT ACCOUNTING A GUIDE TO CONSTRAINT MANAGEMENT THROUGHPUT ACCOUNTING A GUIDE TO CONSTRAINT MANAGEMENT
More informationbridging the leadership divide
frequently asked questions bridging the leadership divide Building High-Performance Leadership Relationships Across Generations Ron A. Carucci, Josh Epperson, and Lela Tepavac Copyright 2010 by Ron Carucci,
More informationBioengineering (BIOE)
Bioengineering (BIOE) 1 Bioengineering (BIOE) Courses BIOE 5301. Biosignals. 3 Credit Hours. This course offers a deep overview of the signals in the Biomedical fields. Signals are studied in several modalities,
More informationManaging the Unexpected
Managing the Unexpected Managing the Unexpected Sustained Performance in a Complex World Third Edition Karl E. Weick Kathleen M. Sutcliffe Cover image: istock.com / ImageGap Cover design: Wiley Copyright
More informationBecoming a Strategic Leader
Becoming a Strategic Leader Join us at josseybass.com Becoming a Strategic Leader Your Role in Your Organization s Enduring Success Second Edition Richard L. Hughes Katherine Colarelli Beatty David L.
More informationP1: OTA/XYZ P2: ABC JWBT502-fm JWBT502-Bern May 5, :14 Printer Name: To Come INVESTING IN ENERGY i
INVESTING IN ENERGY Since 1996, Bloomberg Press has published books for financial professionals on investing, economics, and policy affecting investors. Titles are written by leading practitioners and
More informationJohn Wiley & Sons, Inc.
John Wiley & Sons, Inc. Copyright 2012 byken Schwaber and Jeff Sutherland. All rightsreserved. Published by John Wiley& Sons, Inc., Hoboken, NewJersey. Published simultaneouslyin Canada. No part of this
More informationTHE TRAINER S BALANCED SCORECARD. Ajay M. Pangarkar Teresa Kirkwood. Foreword by Dr. David Norton
Essential resources for training and HR professionals THE TRAINER S Ajay M. Pangarkar Teresa Kirkwood Foreword by Dr. David Norton BALANCED SCORECARD A Complete Resource for Linking LEARNING to ORGANIZATIONAL
More informationFlood Pulsing in Wetlands: Restoring the Natural Hydrological Balance edited by Beth A. Middleton National Wetlands Research Center, USGS, Lafayette,
Flood Pulsing in Wetlands: Restoring the Natural Hydrological Balance edited by Beth A. Middleton National Wetlands Research Center, USGS, Lafayette, Louisiana John Wiley & Sons, Inc. Flood Pulsing in
More informationWHAT S THE SECRET? World-Class. To Providing a. Customer Experience. John R. DiJulius III. John Wiley & Sons, Inc.
WHAT S THE SECRET? To Providing a World-Class Customer Experience John R. DiJulius III John Wiley & Sons, Inc. WHAT S THE SECRET? To Providing a World-Class Customer Experience John R. DiJulius III John
More informationENGINEERING INNOVATIVE PRODUCTS
ENGINEERING INNOVATIVE PRODUCTS ENGINEERING INNOVATIVE PRODUCTS A PRACTICAL EXPERIENCE Edited by Roger Woods Karen Rafferty Julian Murphy School of Electronics, Electrical Engineering and Computer Science,
More informationCommunication and Implementation Sustaining the Practice
Communication and Implementation Sustaining the Practice Jack J. Phillips, Ph.D. Wendi Friedman Tush, M.B.A. About This Book Why This Book Is Important Communication and Implementation: Sustaining the
More informationDNA Microarray Technology and Data Analysis in Cancer Research Downloaded from
This page intentionally left blank Shaoguang Li University of Massachusetts Medical School, USA Dongguang Li Edith Cowan University, Australia World Scientific N E W J E R S E Y L O N D O N S I N G A P
More information