Introduction to Biosensors. Prof. Xingwei Wang
|
|
- Thomas Bryan
- 6 years ago
- Views:
Transcription
1 Introduction to Biosensors Prof. Xingwei Wang 1
2 Brain Storm What do you think of biosensor? 2
3 Brain Storm What do you think of biosensor? 3
4 Significance & Great Demands Civil defense Food safety Criminology Environmental Monitoring Public Health Pathology 4
5 Brief History 1956, Prof. Clark, Father of biosensor concept, Invention of the oxygen electrode 1962, First description of a biosensor 1972/5, First commercial biosensor: Yellow Springs Instruments glucose g biosensor 1975, First immunosensor 1980, First fibre optic ph sensor for in vivo blood gases 1983, First surface plasmon resonance (SPR) immunosensor 1987, Launch of the MediSense ExacTech blood glucose biosensor 1990, Launch of the Pharmacia BIACore SPR-based biosensor system 1992, i-stat i launches hand-held held blood analyser 1996, Abbott acquires MediSense for $867 million 1998, Launch of LifeScan FastTake blood glucose biosensor 1998, Merger of Roche and Boehringer Mannheim to form Roche Diagnostics 2001, LifeScan purchases Inverness Medical's glucose testing business for $1.3billion 5
6 What is a Biosensor A device that uses biological components e.g. enzymes to indicate the amount of a biomaterial Trace biomaterial? Quantitative results? Unnecessary (Eg. Metal ion, etc.) Unnecessary (Eg., Pregnancy test) 6
7 Components Bio Recognition Element Transducer Signal Output Requires: Sample Immobilization Enzymes; Antibodies; Receptors; Whole cells... Electrochemical Optical Requires: Simple read out and data interpretation; Easy to use; Quick response. 7
8 Performance Factors Sensitivity: Concentration; weight Specificity/Selectivity: discriminate between substrates Speed: Bench->Chip >Chip->Real >Real Time Accuracy: False signal Cost Easy to use Life time 8
9 Biosensing for Macromolecules Steps: Immobilization Mixing Washing the non-specific bindings Signal transduction Markers: Enzymes Fluorescence tags Radioactive tags Molecular: Waston-Crick Base pairing Antibody-Antigen Antigen binding 9
10 Immunosensor Antibody can be against Bacteria Complex carbohydrates Smaller organic molecules 10
11 DNA Complementary Chains A Four nitrogen bases Complementary chains T G C C A G T 11
12 Six Steps 1) Select the single-stranded stranded capture DNA sequence 2) Attach the capture DNA strand to a probe 3) Introduce the samples to be identified to the probes 4) Hybridization will occur if the sample is complementary with the capture sequence on the probe 5) Wash away the remaining unattached samples 6) Judgment 12
13 Transducer Electrochemical (Potentiometric, Voltammetric, Amperometry, Conductimetric) Optical (Fluorescence, Absorbance, Light scattering, Refractive index) Mechanical, Thermal, Piezoelectric, Magnetic 13
14 Glucose Sensor 14
15 Microcantilevers From 15
16 Medical Telesensor An array of chips to monitor body functions Wireless transmission Military: Locate wounded soldiers Domestic: Intensive patients From 16
17 Miniaturization Infrared microspectrometer Size of a sugar cube From 17
18 Broad Potential Applications Warfighter Physiological Status Monitoring (WPSM): remote triage of injured Soldiers Heart rate, breaths taken, skin temperature and ballistic impact Foster-Miller (Waltham, Mass.) Putting these sensors on a belt that's sewn into a shirt (Picture from 18
19 Benefits Academia Biosensor Industry Military 19
20 Challenges and Trend Cost Sensitivity Selectivity Speed Small? Ease to use? Cheap Sensitive Selective Speed Portable Simple Integrated Mass produced Multiple analytes 20
21 Multidisciplinary Nature Optics Market Biology Electronics Biosensor Chemistry Instrumentation Physics 21
22 Worldwide Biosensor Vendor Market,
23 References (Reading List 1) sens.htm m m Sensors in Biomedical applications - fundamentals, technology and applications, by Gabor Harsanyi, ISBN: , CRC Press;
24 Education Who I am? MS, Ph.D., Electrical Engineering Virginia Tech Certificate, Future Professoriate Virginia Tech Contact Office Hours: Wednesday 3:30 am 5:30 pm; or, make an appointment Phone: Office: BL 421A Xingwei_Wang@uml.edu 24
25 Syllabus tm The account name: Class_Wang Password: Circuit34567 Literature Review Report Presentation 25
26 Grading Policy Attendance 10% Presentation I 10% Report I 10% Presentation II 10% Report II 10% Final Presentation 25% Final Report/Project 25% Total 100% 26
27 Project topics 1. Ultrahigh sensitive biosensors 2. Fast response biosensors 3. In-vivo blood pressure sensor (St. Jude Medical) 4. Intravascular ultrasound imaging (IVUS) (Volcano) 5. Biosensor integration/miniaturization 6. Optical coherence tomography (OCT) 7. Glucose sensor 8. Nano-Biosensor 27
28 Class Schedule Tentative. Please check frequently for updates. Lecture topics do NOT necessarily follow the order of the schedule. Topic contents may need more or less time than what is allocated. 28
29 About You You are? 29
Amperometric Biosensors. Rahul N 04/10/2014
Amperometric Biosensors Rahul N 04/10/2014 Biosensor A biosensor is an analytical device, used for the detection of an analyte, that combines a biological component with a physicochemical detector. Bio-recognition
More information(General principles and applications)
BIOSENSOR (General principles and applications) Jayanti Tokas, PhD 1 ; Rubina Begum PhD 1 ; Shalini Jain, PhD 2 and Hariom Yadav, PhD 2* 1 Department of Biotechnology, JMIT, Radaur, India; 2 NIDDK, National
More informationIntroduction of Biosensors
Introduction of Biosensors Lecture April 17 Jeff T.H.Wang website: http://pegasus.me.jhu.edu/~thwang/ New course : BioMEMS and BioSensing (Spring 04 ) What s is a biosensor? Target 4.22 Signal Signal Analtye
More informationIntroduction to Biosensor. Wei Shi DianHong Shi
Introduction to Biosensor Wei Shi DianHong Shi Outline The definition of biosensor The history of biosensor The development of biosensor The working principle of biosensor The application of the biosensors
More informationWEARABLE BIOSENSOR Submitted in partial fulfillment of the requirement for the award of degree Of Electronics
A Seminar report On WEARABLE BIOSENSOR Submitted in partial fulfillment of the requirement for the award of degree Of Electronics SUBMITTEDTO: SUBMITTED BY: www.studymafia.org www.studymafia.org Preface
More informationLecture FO7 Affinity biosensors
Lecture FO7 Affinity biosensors Dr. MAK Wing Cheung (Martin) Biosensors & Bioelectronic Centre, IFM Email: mamak@ifm.liu.se Phone: +4613286921 (21 Feb 2014) Affinity biosensors Affinity biosensors: devices
More information2.3 Quantum Dots (QDs)
2.3 Quantum Dots (QDs) QDs are inorganic nanocrystals, approximately 1 10 nm in size, with unique optical properties of broad excitation, narrow size-tunable emission spectra, high photochemical stability,
More informationEUROSENSORS SCHOOL. School chair: Péter Fürjes, PhD (MFA, Budapest)
1 EUROSENSORS SCHOOL School chair: Péter Fürjes, PhD (MFA, Budapest) Advisors: Prof. Arnaldo D Amico (Uni Roma) and Prof. Pasqualina M. Sarro (TU Delft) September 4, 2016, Budapest Congress Centre 2 TRENDS
More informationBio MEMS Class -1 st week
Bio MEMS Class -1 st week Jang, Jaesung Ref: Bashir ADDR Review paper, 2004. 1 Introduction Bio-MEMS: devices or systems, constructed using techniques inspired from micro/nano-scale fabrication, that are
More informationNanobiosensor. Chennai, Tamil Nadu, India. Mumbai, Maharashtra, India. Abstract
Advance in Electronic and Electric Engineering ISSN 2231-1297, Volume 3, Number 3 (2013), pp. 321-326 Research India Publications http://www.ripublication.com/aeee.htm Nanobiosensor M. Naveen Kumar Reddy
More informationVarioustypes of transducing elements and their applications in Bio-Nanotechnology
Varioustypes of transducing elements and their applications in Bio-Nanotechnology Abstract Nanotechnology plays an important role in the development of biosensors. The sensitivity and performance of biosensors
More informationCommercial Biosensors
Commercial Biosensors MB-JASS 2006 Nathalie Munnikes, TUM Commercial Biosensors - Nathalie Munnikes - TUM 1 What is a biosensor? Overview The biological component Immobilization Some transducer principles
More informationBiophotonics?? Biophotonics. technology in biomedical engineering. Advantages of the lightwave
Biophotonics - Imaging: X-ray, OCT, polarimetry, DOT, TIRF, photon migration, endoscopy, confocal microscopy, multiphoton microscopy, multispectral imaging - Biosensing: IR spectroscopy, fluorescence,
More informationAbsorption of an electromagnetic wave
In vivo optical imaging?? Absorption of an electromagnetic wave Tissue absorption spectrum Extinction = Absorption + Scattering Absorption of an electromagnetic wave Scattering of an electromagnetic wave
More informationElectrochemical biosensors-a Review
Electrochemical biosensors-a Review Annalen der Chemischen Forschung Vol-2: No-1: 36-40: 2014 Mohamed Sikkander A Department of Chemistry, Velammal Engineering College, Chennai- 600018, Tamil Nadu, India
More informationEnzyme based biosensors
Enzyme based biosensors Brief history; how it all started? 1916 First report on immobilization of proteins : adsorption of invertase on activated charcoal 1922 First glass ph electrode 1956 Clark published
More informationBEE 4590/6590 Biosensors and Bioanalytical Techniques
BEE 4590/6590 Biosensors and Bioanalytical Techniques Fall Semester 2008 105 Riley-Robb Hall Antje Baeumner 318 Riley-Robb Hall ajb23@cornell.edu Lectures: Office hours Tuesday, Thursday 1.25 2.40 p.m.
More informationBiosensor Technology - an overview
Biosensor Technology - an overview Lars H. Pedersen Lars Lading October 6. 2005 Bioneer in short Contract Research and Development within Biotechnology & Biomedicine Molecular detection Vaccine technology
More informationLecture2.2 Biosensor
Lecture2.2 Biosensor Biological and biochemical processes have a very important role on medicine, biology and Biotechnology. The first biosensor was described in 1962 by Clark and Lyons who immobilized
More informationBiosensor Principles and Applications BE/MBBE 625, Spring 2008 Course Syllabus Instructor: Daniel M. Jenkins Meeting Time and Location Grading:
Biosensor Principles and Applications BE/MBBE 625, Spring 2008 Course Syllabus Instructor: Daniel M. Jenkins Office: Agricultural Science 415L Telephone: 956-6069 Office Hours: Thursday 4-5 PM & by appointment
More informationIntroduction to Biomedical Engineering
Introduction to Biomedical Engineering Biomedical sensors Kung-Bin Sung 5/21/2007 1 Outline Chapter 9: Biomedical sensors Biopotential measurements Physical measurements Chemical measurements Blood gases
More informationJordan University of Science and Technology Faculty of Engineering Biomedical Engineering Department. BME 510- Biomedical Sensors and Transducers
Jordan University of Science and Technology Faculty of Engineering Biomedical Engineering Department BME 510- Biomedical Sensors and Transducers Course Catalog 3 Credit hours (3 h lectures). Introduction
More informationCase Studies of Micro-Biosensors
Case Studies of Micro-Biosensors Lecture April 18 Jeff T.H.Wang website: http://pegasus.me.jhu.edu/~thwang/ New course : BioMEMS and BioSensing (Spring 04 ) Advantages of Micro Biosensors Bench process
More informationModule: Key Enabling Technologies for Biomedical Engineering
Module: Key Enabling Technologies for Biomedical Engineering Mandatory Courses New Frontiers in Medical Technology Coordinator: Laura González Credits: 6 This course offers an up-to-date report on current
More informationElectrochemical Sensors
Introduction to BioMEMS & Medical Microdevices Sensor Principles and Microsensors Part 2 Companion lecture to the textbook: Fundamentals of BioMEMS and Medical Microdevices, by Prof., http://saliterman.umn.edu/
More informationBIOSENOSRS BIO 580. Nanobiosensors WEEK-13 Fall Semester. Faculty: Dr. Javed H. Niazi KM Faculty of Engineering & Natural Sciences Sabanci University
BIOSENOSRS BIO 580 Nanobiosensors WEEK-13 Fall Semester Faculty: Dr. Javed H. Niazi KM Faculty of Engineering & Natural Sciences Sabanci University Topics that will be covered in the course History of
More informationOptical Fiber Sensors for Biomedical Applications
Optical Fiber Sensors for Biomedical Applications Xingwei (Vivian) Wang, Ph.D. Assistant Professor Department of Electrical and Computer Engineering University of Massachusetts Lowell Phone: (978) 934-1981
More informationSensor Principles and Microsensors Part 2
Introduction to BioMEMS & Medical Microdevices Sensor Principles and Microsensors Part 2 Companion lecture to the textbook: Fundamentals of BioMEMS and Medical Microdevices, by Prof., http://saliterman.umn.edu/
More informationMACROMOLECULAR AFFINITY CHARACTERIZATION FACILITY. India. There are 4 instruments in the facility. They are Biacore2000,
MACROMOLECULAR AFFINITY CHARACTERIZATION FACILITY DIVISION OF BIOLOGICAL SCIENCES INDIAN INSTITUTE OF SCIENCE S P ABOUT This facility was established in 1997 with support from DBT, Govt. of India. There
More informationBIOMEDICAL SIGNAL AND IMAGE PROCESSING
BIOMEDICAL SIGNAL AND IMAGE PROCESSING EE 5390-001 SYLLABUS Instructor: Wei Qian, Ph.D. Professor of Electrical and Computer Engineering Medical Signal and Image Computerized Processing Scheme for Medical
More informationPathogen Biosensors. Randy Yao, Samantha Williams
1 Pathogen Biosensors Randy Yao, Samantha Williams 2 Pathogens (GERMS) Pathogens are: anything that causes disease in its host. Examples: Bacteria, Virus, Fungus, Prion More well known as "germs". 3 Presentation
More informationDNA Biosensors. Anand Jagota 16 November 2015
DNA Biosensors Anand Jagota 16 November 2015 1 Market, Unmet Needs Worldwide In-vitro diagnostics ~$ 50 Billion and growing Nucleic Acid diagnostics ~$9 Billion Health, Security, Pathogen Detection, etc.
More informationNanyang Technological University Division of Physics and Applied Physics
Academic Year AY1819 Semester 1 Course Coordinator Asst. Prof (Adj) Dinish U. S Course Code PH4607/ CM4017 Course Title Biomedical Imaging and Sensing Pre-requisites PH2301 Physical Optics (for PHY) OR
More informationBiosensors. Introduced by Elena Neufeld Dec 8 th 2010
Biosensors Introduced by Elena Neufeld Dec 8 th 2010 One of the first 'biosensors' To detect gas build-ups in coal mines, caged canaries were used because of their sensitivity towards methane. biological
More informationMEDICAL EQUIPMENT (1) TOPIC 1: RECORDING AND PROCESSING OF BIOSIGNALS
MEDICAL EQUIPMENT (1) TOPIC 1: RECORDING AND PROCESSING OF BIOSIGNALS Term 1 2013/14 Prof. Yasser Mostafa Kadah www.k-space.org Measurement Basics Measuring is the experimental determination of a measured
More informationChE 125. Principles of Bioengineering
ChE 125 Principles of Bioengineering ChE 125 Instructor: Prof. Samir Mitragotri Room 3349, Engineering II Email: samir@engineering.ucsb.edu Office Hours: Tuesday 1-2 pm Teaching Assistant: Aaron Anselmo
More informationDesign of Integrated Mixed Technology Microsystems. Microsystems Technology Office. DARPATECH September 2000
Design of Integrated Mixed Technology Microsystems Anantha Krishnan TECH September 2000 Technology Trends SYSTEM COMPLEXITY IS INCREASING!! DESIGN AND PROTOTYPING COSTS ARE INCREASING AT A GREATER RATE
More information7/24/2012. DNA Probes. Hybridization and Probes. CLS 420 Immunology & Molecular Diagnostics. Target Sequences. Target Sequences. Nucleic Acid Probes
Hybridization and Probes CLS 420 Immunology & Molecular Diagnostics Molecular Diagnostics Techniques: Hybridization and Probes Nucleic acid probes: A short, known sequence of DNA or RNA Used to detect
More informationSyllabus for BIEN 167: Medical Diagnostics
Syllabus for BIEN 167: Medical Diagnostics Prof. William Grover (wgrover@engr.ucr.edu) Fall 2015 Class Schedule Lecture: 9:10 10:00 MWF SPR 1340 Discussion: 8:10 9:00 T MSE 003 Course description Provides
More informationAbstract of the seminar Commercial Biosensors (MB-JASS 2006)
Abstract of the seminar Commercial Biosensors (MB-JASS 2006) 1 Introduction A biosensor is a device, which uses a biological component to determine the concentration of a certain substance. Apart from
More informationNanostructured Plasmonic Interferometers for Ultrasensitive Label-Free Biosensing. Fil Bartoli Lehigh University 4/9/2014
Nanostructured Plasmonic Interferometers for Ultrasensitive Label-Free Biosensing Fil Bartoli Lehigh University 4/9/2014 P.C. Rossin College of Engineering and Applied Science Department of Electrical
More informationClick here to enlarge image
1 of 6 6/2/2003 10:19 AM Amanda Haes Richard Van Duyne Nanosensors enable portable detectors for environmental and medical applications The development of biosensors for the diagnosis and monitoring of
More informationProperties of nanofabricated biosensors based on DNA aptamers
Properties of nanofabricated biosensors based on DNA aptamers Tibor Hianik Faculty of Mathematics, Physics and Computer Sci., Comenius University, Bratislava, Slovakia Content of presentation Introduction
More informationSensor. Device that converts a non-electrical physical or chemical quantity into an electrical signal. Sensor Processor Display Output signal
Microsensors Outline Sensor & microsensor Force and pressure microsensors Position and speed microsensors Acceleration microsensors Chemical microsensors Biosensors Temperature sensors Sensor Device that
More informationSurface Plasmons and Their Bio- Applications
Surface Plasmons and Their Bio- Applications Pei-Kuen Wei Associate Research Fellow, Research Center for Applied Sciences Academia Sinica, Taipei, Taiwan Outline 1. Introduction to Immunoassay 2. Surface
More informationWelcome - Sensors - Red Hot Chillies to Patients
Welcome - Sensors - Red Hot Chillies to Patients 2018 What do sensors mean for We like measuring things and sensing things? Workshop content 1. Introductions 2. Cyclic voltammetry through Chilli Sensing
More informationchapter 10 Bioelectronics
chapter 10 Bioelectronics Contents Introduction................................................................ Biosensors.................................................................. Biochips....................................................................
More informationVeterinary Medicine TABLE 6 BIOSENSOR APPLICATIONS IN VETERINARY MEDICINE FOOD PRODUCTION TABLE 7 FOOD PRODUCTION APPLICATIONS OF
INTRODUCTION... XX STUDY GOAL AND OBJECTIVES... XX REASONS FOR DOING THE STUDY... XX CONTRIBUTION OF THE STUDY AND FOR WHOM... XXI SCOPE AND FORMAT... XXI METHODOLOGY AND INFORMATION SOURCES... XXII ANALYST
More informationNanodiagnostics By Kaizan Kalyaniwalla
Nanodiagnostics By Kaizan Kalyaniwalla What if there was a way doctors could determine your likelihood of contracting a disease without you actually acquiring the symptoms of that disease? Current diagnostic
More informationLETI-HEALTH. Adrienne Pervès Deputy Director LETI Technologies for Biology and healthcare Department
Adrienne Pervès adrienne.perves@cea.fr Deputy Director LETI Technologies for Biology and healthcare Department LETI-HEALTH Micro- NanoTechnologies for Healthcare and Biology MISSION AND EXPERTISE Focused
More informationIMEC R&D PLATFORMS APPLICATION DOMAINS SEMICONDUCTOR & SYSTEM TECHNOLOGIES DIGITAL TECHNOLOGY PLATFORMS
IMEC R&D PLATFORMS APPLICATION DOMAINS SMART HEALTH SMART MOBILITY SMART CITIES SMART INDUSTRIES SMART ENERGY SEMICONDUCTOR & SYSTEM TECHNOLOGIES DIGITAL TECHNOLOGY PLATFORMS CORE CMOS SENSOR TECHNOLOGY
More informationMulti Way Biosensors: Development and Commercialization
B2.2 Multi Way Biosensors: Development and Commercialization Zahn, Dorothea; Szeponik, Jan; Gandhi, Adrian BST Bio Sensor Technology GmbH Buchholzer Strasse 55-61, 13156 Berlin, Germany Introduction The
More informationOpenPlex. Multiplex Label-Free Interaction Analysis. Open Research Platform
OpenPlex Multiplex Label-Free Interaction Analysis Open Research Platform OpenPlex Get information about: Kinetics Affinity Specificity Concentration Relative binding OpenPlex is the ideal solution for
More informationBiochemistry 9/1/17. Course No: CHM4006; Credits: Day / Time: Wednesday & Friday: 13:30-15:00. Ro # H & 208 (IT/BT)
You Do Not Need to write down the following infos because all the following slides and all lecture notes will be uploaded at the link: http://itbe.hanyang.ac.kr This/today s file will be uploaded next
More informationExploring metallic nanoparticles in Biophotonics
Exploring metallic nanoparticles in Biophotonics Renato E. de Araujo Laboratório de Óptica Biomédica e Imagem, Universidade Federal de Pernambuco Recife, PE, Brazil. renato.earaujo@ufpe.br LABORATÓRIO
More informationBME Course Descriptions
BME Course Descriptions 2018-19 BIM 1 Introduction to Biomedical Engineering Units: 2 Fall Lecture: 1 hour; Laboratory: 3 hours. No prerequisite. Introduction to the field of biomedical engineering with
More informationAPPLICATION OF MOLECULAR TECHNICS FOR DIAGNOSIS OF VIRAL INFECTIONS
APPLICATION OF MOLECULAR TECHNICS FOR DIAGNOSIS OF VIRAL INFECTIONS Hossein Keyvani Basic Diagnostic Methods in Virology Immunology and serology techniques (Antigen-Antibody Reactions) 1 ELISA ( Enzyme
More informationElectrochemical Sensors
Electrochemical Sensors Arthur Gildea ABC s of Electrochemistry 1/26/2012 Overview Introduction Reference electrode Biosensors and Immunosensors Potentiometric sensor Amperometric sesnor Conductometric
More informationCharacterization of Aptamer Binding using SensíQ SPR Platforms
Characterization of Aptamer Binding using SensíQ SPR Platforms APPLICATION NOTE INTRODUCTION Aptamers have the potential to provide a better solution in diagnostics and other research areas than traditional
More informationUNCLASSIFIED R-1 ITEM NOMENCLATURE
COST ($ in Millions) All Prior FY 2014 Years FY 2012 FY 2013 # Base FY 2014 FY 2014 OCO ## Total FY 2015 FY 2016 FY 2017 FY 2018 Cost To Complete Total Program Element - 44.445 39.676 49.500-49.500 51.500
More informationBIOSENSORS: PRINCIPLE, TYPES AND APPLICATIONS
BIOSENSORS: PRINCIPLE, TYPES AND APPLICATIONS Shagun Malhotra 1, Abhishek Verma 2, Naveen Tyagi 3, Vivek Kumar 4 1 Electronics Design Engineer (R&D Deptt.), Vinytics Peripherals Pvt. Ltd, New Delhi, India
More informationFuture Areas of Technology Convergence
Future Areas of Technology Convergence Dr J Malcolm Wilkinson Managing Director Technology For Industry Ltd Cambridgeshire, UK Medilink Yorkshire & Humberside, 8 December 2005 1 Technology For Industry
More informationBiomarker Discovery using Surface Plasmon Resonance Imaging
F e a t u r e A r t i c l e Feature Article Biomarker Discovery using Surface Plasmon Resonance Imaging Elodie LY-MORIN, Sophie BELLON, Géraldine MÉLIZZI, Chiraz FRYDMAN Surface Plasmon Resonance (SPR)
More informationNanophotonics: principle and application. Khai Q. Le Lecture 11 Optical biosensors
Nanophotonics: principle and application Khai Q. Le Lecture 11 Optical biosensors Outline Biosensors: Introduction Optical Biosensors Label-Free Biosensor: Ringresonator Theory Measurements: Bulk sensing
More informationSensors. May
Sensors May 18 2005 1 Future Technology Center Technology Trends Statistical trend analysis of technologies (patents & papers) and markets Analysis and assessment of industrial roadmaps Workshops with
More informationIntegrated photonic devices for sensing and optical communication in the near- and mid- IR
Integrated photonic devices for sensing and optical communication in the near- and mid- IR Dr. Senthil M Ganapathy (smg@orc.soton.ac.uk) Prof. James S Wilkinson (jsw@orc.soton.ac.uk) Motivation: Integrated
More informationSurface Plasmon Resonance Analyzer
Surface Plasmon Resonance Analyzer 5 6 SPR System Based on Microfluidics Wide Dynamic Range Kinetic Analysis by Detection of Association /Dissociation of Bio-Molecules Measuring of Mass Change below
More informationSURFACE PLASMON RESONANCE-BASED SYSTEMS
SURFACE PLASMON RESONANCE-BASED SYSTEMS ADVANCED METHODS IN BIOENGINEERING LABORATORY 3/1/2011 1 Schedule Week 1: Introduction Reagents preparation Ligand immobilization of Protocol 1 Week 2: Kinetics
More informationAPPLICATIONS OF BIOSENSORS IN CLINICAL BIOCHEMISTRY
APPLICATIONS OF BIOSENSORS IN CLINICAL BIOCHEMISTRY Dr. Rohini Karunakaran Associate Professor, Unit of Biochemistry Preclinical Coordinator Acting Head Medical Education Unit Faculty of Medicine AIMST
More informationPrecise. Flexible. Robust. Affordable.
Maximum versatility to match current and future research needs for interaction analysis Small Molecules Crude Samples Whole Cells Viruses Lysates Serum Immunogenicity Protein & Antibodies Nanoparticles/Nanomaterials
More informationDEVELOPMENT OF A FIELDABLE, RAPID, ACCURATE & SENSITIVE BIO-ELECTRONIC, DNA BIOSENSOR
DEVELOPMENT OF A FIELDABLE, RAPID, ACCURATE & SENSITIVE BIO-ELECTRONIC, DNA BIOSENSOR Michael Connolly*, Ph.D, David Chafin, Ph.D, and Doyle Hill, Ph.D Integrated Nano-Technologies Henrietta, NY 14467
More informationScience of Living Systems (ML 201) Second Year B. Tech. Program
Science of Living Systems (ML 201) Second Year B. Tech. Program Teaching Scheme Lectures : 3 lectures/week Examination Scheme (Marks M) T1-20 M (Classroom activity),t2-20 M (Assignment/s) Semester End
More informationPhotonic Crystal Microarray Nanoplatform for High-Throughput Detection of Biomolecules
Photonic Crystal Microarray Nanoplatform for High-Throughput Detection of Biomolecules Swapnajit Chakravarty 1, Wei-Cheng Lai 2, Kathryn Moncivais 3, Xiaolong (Alan) Wang 1, Che-Yun Lin 2, Zhiwen J. Zhang
More informationNanosensors. Rachel Heil 12/7/07 Wentworth Institute of Technology Department of Electronics and Mechanical Professor Khabari Ph.D.
Nanosensors Rachel Heil 12/7/07 Wentworth Institute of Technology Department of Electronics and Mechanical Professor Khabari Ph.D. There are many advances in nanotechnology that if perfected could help
More informationBiosensors. DNA Microarrays (for chemical analysis) Protein Sensors (for identifying viruses)
Biosensors DNA Microarrays (for chemical analysis) Protein Sensors (for identifying viruses) DNA Microarrays 40 000 detectors in parallel, each detecting a specific DNA sequence. Combinatorial Chemistry
More informationSGN-6106 Computational Systems Biology I
SGN-6106 Computational Systems Biology I A View of Modern Measurement Systems in Cell Biology Kaisa-Leena Taattola 21.2.2007 1 The cell a complex system (Source: Lehninger Principles of Biochemistry 4th
More informationBIOMEDICAL ENGINEERING SOPHOMORE DESIGN AND RESEARCH I BIOMEDICAL ENGINEERING SOPHOMORE DESIGN AND RESEARCH II
Course Descriptions by Department/Program Biomedical Engineering BIOMEDICAL ENGINEERING SOPHOMORE DESIGN AND RESEARCH I BME 0003 BIOMEDICAL ENGINEERING SOPHOMORE DESIGN AND RESEARCH II BME 0004 BIOMEDICAL
More informationOmniCure Assembly Solutions
OmniCure Assembly Solutions Biosensors Challenge Repeatable, low cost, assembly of biosensors. Solution The OmniCure S2000 UV spot curing system with Closed-Loop Feedback technology using a light curable
More informationDate: May 26, 2015 Page 1
Part I. Answer these questions by marking the best answer among the choices given: [2 points each] 1. Ethics and morals differ in that a. Only one of them should be followed b. Ethics are for professionals
More informationWeb Based Photonic Crystal Biosensors for Drug Discovery & Diagnostics
Web Based Photonic Crystal Biosensors for Drug Discovery & Diagnostics Stephen C. Schulz Introduction SRU Biosystems Inc., Woburn MA Biosensors, Instruments, Software, and Applications Drug Discovery and
More informationPERIYAR UNIVERSITY SALEM CERTIFICATE IN RADIO IMAGE TECHNOLOGY (1Years) SYLLABUS / REGULATIONS. Annexure - 14
PERIYAR UNIVERSITY SALEM 636 011. Annexure - 14 PERIYAR INSTITUTE OF DISTANCE EDUCATION [PRIDE] CERTIFICATE IN RADIO IMAGE TECHNOLOGY (1Years) SYLLABUS / REGULATIONS [Candidates admitted from 2007-2008
More informationGE Healthcare Life Sciences. A year of interaction with Biacore X100
GE Healthcare Life Sciences A year of interaction with Biacore X1 Protein interaction research Real-time monitoring of binding events using surface plasmon resonance (SPR) gives a deep understanding of
More informationDirect genotyping of C3435T single nucleotide polymorphism in unamplified human MDR1 gene using a surface plasmon resonance imaging DNA sensor
Analytical and Bioanalytical Chemistry Electronic Supplementary Material Direct genotyping of C3435T single nucleotide polymorphism in unamplified human MDR1 gene using a surface plasmon resonance imaging
More informationA New Cellular and Molecular Engineering Curriculum at Rice University
Session A New Cellular and Molecular Engineering Curriculum at Rice University Ka-Yiu San, Larry V. McIntire, Ann Saterbak Department of Bioengineering, Rice University Houston, Texas 77005 Abstract The
More informationSelected Techniques Part I
1 Selected Techniques Part I Gel Electrophoresis Can be both qualitative and quantitative Qualitative About what size is the fragment? How many fragments are present? Is there in insert or not? Quantitative
More informationChemistry Notices. Submissions: Please send to by Wednesday for the following week s edition
Chemistry Notices For the Week of March 6 to March 10, 2017 Submissions: Please send to newsletter@chem.ualberta.ca by Wednesday for the following week s edition VISITING SPEAKERS AND SEMINARS Matthew
More informationCHAPTER 24. Immunology
CHAPTER 24 Diagnostic i Microbiology and Immunology Growth-Dependent Diagnostic Methods Isolation of Pathogens from Clinical Specimens Proper sampling and culture of a suspected pathogen is the most reliable
More informationPortable Biomedical Diagnostic Inspection System using BioCMOS technology
1 Portable Biomedical Diagnostic Inspection ystem using BioCMO technology BioCMO http://biocmos.com Office Japan & ingapore Phone +65 654362 E-mail ayee@technofront.net 7.49mm Booth #33 (Nagoya University)
More informationDeoxyribonucleic Acid DNA
Introduction to BioMEMS & Medical Microdevices DNA Microarrays and Lab-on-a-Chip Methods Companion lecture to the textbook: Fundamentals of BioMEMS and Medical Microdevices, by Prof., http://saliterman.umn.edu/
More informationIntroduction to BioMEMS & Medical Microdevices DNA Microarrays and Lab-on-a-Chip Methods
Introduction to BioMEMS & Medical Microdevices DNA Microarrays and Lab-on-a-Chip Methods Companion lecture to the textbook: Fundamentals of BioMEMS and Medical Microdevices, by Prof., http://saliterman.umn.edu/
More informationChapter 10 Analytical Biotechnology and the Human Genome
Chapter 10 Analytical Biotechnology and the Human Genome Chapter Outline Enzyme tests and biosensors DNA-based tests DNA analysis technologies Human genome and genome-based analytical methods 1 Enzyme-based
More informationCourse Code: BMEG5100 Course Title: Advanced Medical Robotics Course Code: BMEG5110 Course Title: Advanced Medical Devices and Sensor Networks
Course Code: BMEG5100 Course Title: Advanced Medical Robotics Review of medical robotics fundamentals; introduction to robotics enabled endoscopic and laparoscopic surgeries; concepts of robotics based
More informationComputational methods in bioinformatics: Lecture 1
Computational methods in bioinformatics: Lecture 1 Graham J.L. Kemp 2 November 2015 What is biology? Ecosystem Rain forest, desert, fresh water lake, digestive tract of an animal Community All species
More informationDirected Assembly of Nanoparticles for Biosensing Applications
NSF Nanoscale Science and Engineering Center for High-rate Nanomanufacturing (CHN) www.nano.neu.edu Directed Assembly of Nanoparticles for Biosensing Applications Ahmed Busnaina, Director, NSF Nanoscale
More informationFUNDING OPPORTUNITIES FAIRE: NATIONAL INSTITUTES OF HEALTH
FUNDING OPPORTUNITIES FAIRE: NATIONAL INSTITUTES OF HEALTH ERC Biennial Meeting Theme: Preparing Tomorrow s Leaders October 28, 2014 Grace C.Y. Peng, Ph.D. The NIH Mission NIH is the steward of medical
More informationThis is a repository copy of Label-free affinity biosensor arrays : novel technology for molecular diagnostics.
This is a repository copy of Label-free affinity biosensor arrays : novel technology for molecular diagnostics. White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/111980/ Version:
More informationDNA & Protein Biosensors Vishwindera S. Kailey Vivek Govardhanam
BIOSENSORS DNA & Protein Biosensors Vishwindera S. Kailey Vivek Govardhanam 1 OUTLINE OF PRESENTATION Basic Information on DNA. Introduction to Biosensors DNA & Protein biosensors DNA- DNAFET & Southern
More informationInterferometric optical biosensor. Xingwei Wang
Interferometric optical biosensor Xingwei Wang 1 Light Transverse electromagnetic wave Reflection Refraction Diffraction Interference 2 Fabry-Perot interferometer 3 Interferometer Two waves that coincide
More informationEnhancement of electrochemical biosensor performances using redox cycling at 3D sub-micrometer scale electrode architectures.
Enhancement of electrochemical biosensor performances using redox cycling at 3D sub-micrometer scale electrode architectures Heungjoo Shin School of Mechanical and Nuclear Engineering Contents 1 Introduction
More informationThe vast literature in the last 40 years related to the keyword Biosensor reveals without doubt
CHAPTER 2 A Brief Story of Biosensor Technology Marco Mascini* Introduction The vast literature in the last 40 years related to the keyword Biosensor reveals without doubt that the scientific field is
More information