Laboratory Reagents. for life science research.

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1 Laboratory Reagents Research, quality control, or routine analysis whatever the field of activity, where there is a need for laboratory reagents, Thermo Fisher Scientific has a suitable product. We offer a comprehensive portfolio of solvents and reagents for analytical applications and a dynamic range of essential reagents Products LC/MS Solvents UHPLC and HPLC Solvents High-Purity Acids BioReagents Specialized Chemical Services for life science research.

2 The Thermo Fisher Scientific portfolio offers a range of solutions for laboratories engaged in research, development and analysis at any level, from routine analysis to drug toxicology studies, proteomics to environmental testing. Challenges: Maintaining low contamination levels to meet the challenges of chromatography Improving detection limits for the most demanding analytical applications Obtaining accurate, reproducible results faster, safer, and easier

3 Separate, analyze, and identify by LC/MS with the highest level of performance. Thermo Fisher Scientific Products range for LC/MS applications Fisher Chemical Optima LC/MS grade products offer a high level of excellence for consistent, reproducible performance in the mobile phase of LC/MS. Solvents Optima LC/MS grade Mobile Phase Blends Optima LC/MS grade Reagents & Additives Optima LC/MS grade OUR EDGE The certified performance of our Optima LC/MS solvents offers the most reliable solutions for today s scientist.

4 Featured Product Optima LC/MS Solvents: Acetonitrile, Methanol & Water Reach the highest level of LC/MS performance New Improved Key Features Innovative LC-UV Gradient test ensuring extremely low levels of UV-absorbing impurities Peak Height with PDA (from 200 to 400 nm) with 2mAU max Lower particulate levels < 0,1µ filtration to protect columns and components from clogging Higher signal intensity & lower metal ion content (up to 17 metals level tested) UHPLC system suitability Application Proteomics, Pharmaceutical research, Drug Discovery, Biomedical research For routine LC/MS application the LC/MS grade is recommended

5 Featured Product Specialized LC/MS Mobile Phase Blends Key Features Extensive functional testing to ensure reduced metals content to prevent formation of metal adduct and improved analyte formation Innovative packaging composition (borosilicate glass) to ensure solvent integrity Benefits Ready to use avoiding the possibility of contamination during the house blending of solvents Reduce overhead costs associated with preparing blends Pharmaceutical & Clinical Applications Drug Toxicology, Pharmacokinetics, Proteomics, Metabolomics, Endocrinology/Biomarkers, Lipidomics, and Therapeutic Drug Monitoring Main Research Applications Vitamin D assay, Hormone analysis, Immunosuppressant (ISD) and Protein/Peptide analysis

6 Achieve maximum performance in liquid chromatography. Thermo Fisher Scientific UHPLC and HPLC Solvents Fisher Chemical offers a wide range of solvents and reagents to meet the challenges of chromatography: UHPLC Gradient Grade: Outstanding high UV transmission, low baseline noise at 210nm and 254nm, lower acidity/alkalinity level, lower residue after evaporation level, and filtered to 0.1µ. Advanced Gradient Grade: Suitable for HPLC gradient grade pumps for analysis requiring very low baseline (drift baseline tested), featuring low acidity/alkalinity level and filtered to 0.2µ. HPLC Gradient Grade: Suitable for HPLC gradient grade pumps for routine analysis, with high UV transmission, low acidity/alkalinity level, and filtered to 0.2µ. OUR EDGE The Thermo Scientific portfolio offers the instrumentation, equipment, consumables, and reagents to provide accurate, reliable, consistent, and reproducible results regardless of the method of analysis.

7 Optimize the chromatography performance by choosing the suitable Fisher Chemical solvents grade Chromatography Application Instrument and Detector Type Fisher Chemical Solvent Grade High HPLC-MS LC and UHPLC coupled with Mass detector Optima LC/MS HPLC-MS LC coupled with Mass detector LC/MS grade UHPLC UHPLC coupled with UV detector UHPLC gradient grade High HPLC Gradient Grade LC gradient grade coupled with UV detector HPLC Advanced grade HPLC Gradient Grade LC gradient grade coupled with UV detector HPLC gradient grade HPLC LC coupled with UV detector HPLC grade

8 Exceed the detection limit in trace elemental analysis Thermo Fisher Scientific High-Purity Acids Whether analyzing environmental and food samples, etching glass, or conducting routine analysis requiring trace elemental analysis, our Fisher Chemical high-purity acids meet the most challenging applications, including AAS, ICP, and ICP-MS. Optima Acids (1-100ppt): Highest purity, lowest metal content, and suitable for ICP-MS. OUR EDGE Choice, quality, and value are delivered through a comprehensive range of grades developed to meet the requirements of the chosen instrument and technique. Trace Metal Grade (0,1-1ppb): Superior purity, exceptional value, and suitable for ICP. Primar Plus Acids (1-10 ppb): Perfect choice for routine applications.

9 Choose superior quality and valueadded reagents qualified for Fisher BioReagents A dynamic range of essential reagents for life science research: Purity grades that match products to applications Prequalification for specific life science applications Core products for general uses molecular biology, cell biology, and protein chemistry applications. OUR EDGE: Combined with the Fisher Scientific portfolio of life science products, customers can expect true end-toend solutions for molecular biology, protein chemistry, and cell biology applications.

10 Featured Product Grades of Bovine Serum Albumin BSA Fisher BioReagents Key Features Application-specific grades of BSA such as low endotoxin and protease-free grades All BSA products meet rigorous quality control tests including purity, solubility and heavy metal content BSA products are certified US origin Suitable for use as growth supplement in various cell culture systems such as serum-free and microbiological media Microbiological Grade Powder Protease-Free Powder Fatty Acid-Free Powder Low Endotoxin Powder BP9700 BP9703 BP9704 BP9705 BP9706 Culture Media Animal/Insect Cells DNase- and Protease-free Powder Culture Media Microbes Stabilizing/Enhancing Diluent in Enzyme Systems Polymerase Chain Reaction (PCR) Immunohematology Serology RIA Systems Blood Banking Reagents Binding and Transport Studies Protein Base or Filler Protein Standard (MW, Amino Acids, and Nitrogen) ELISA (Blocks Non-Specific Binding) As Carrier Protein for Haptens

11 Take advantage of solvents, reagents, and solutions tailored to individual needs. Thermo Fisher Scientific Specialized Chemical Services Our Specialized Chemical Services (SCS) team serves customers who require something different: Semi-bulk and bulk chemicals Tailored solvents and solvent blends Special solutions Additional testing services Customized packaging and labeling OUR EDGE: We enable our customers to optimize their own resources with our secure and validated global supply chain; global sourcing capabilities; and manufacturing, quality control, and packaging expertise.

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