Workshop 242 TABLET COATING June 2018

Transcription

1 Workshop 242 TABLET COATING June 2018

2 BACKGROUND On the one hand, increasing international competition is forcing companies to optimize their manufacturing and R&D processes. These trends increase quality and efficiency demands especially for the processing of oral solid dose forms as the predominant galenic form. This includes the important step of tablet coating at the end of the process. On the other hand, there are few options to obtain a perfect mix of theoretical and practical training. We want to bridge this gap between business and education with our decades of experience in the manufacture and use of production equipment. What makes our specialized training so special is: THE UNIQUE HANDS-ON APPROACH. WHO SHOULD ATTEND? Operating and research staff employed in the pharmaceutical and other related industries, where compliance to GMP standards, accuracy and reproducibility are absolutely essential.

3 PROGRAM MONDAY, 18 JUNE :00 Transfer from the hotel to the TTC 12:30 Reception & registration 13:00 Introduction. Andreas Gottschalk 13:10 Layout and design of perforated drum coaters for pharmaceutical and related industries. Providing an overview on the typical range of machines used when coating tablets in the various industries. Additionally outlining the required peripheral installations and setup for efficient processes. Bernd Looser 13:50 Optimized film-coating with modern fully formulated film coating systems. Overview of fully formulated coating systems, formulation and design strategies, comparison of the various polymer systems, mechanical and physicochemical properties, applications, customization for troubleshooting. Paul Smith FILM-COATING IN PERFORATED PANS I 14:35 Part 1 Preparation of the Machine: Outlining the influence of batch-size on the setup of the spray guns and the exhaust air shoe. Wolfgang Dejan 15:15 Coffee break FILM-COATING IN PERFORATED PANS II 15:45 Part 2 - Running the Process: Discussing the main (controlled) parameters and the trip conditions for an automated process. Tim Anders 16:30 Excipients for film-coating processes. Overview of the ingredients commonly used in film coating formulations. Nina Hauschildt 17:15 Transfer to hotel 19:30 Workshop dinner

4 TUESDAY, 19 JUNE :15 Transfer to the application laboratory in Pratteln (CH) PRACTICAL SESSION AT THE APPLICATION LABORATORY 09:00 Introduction to the practical part. Bernd Looser 09:15 Practical session I: Experiments in the lab with lab and pilot equipment Wolfgang Dejan, Christopher Scheer 10:45 Coffee break 11:00 Spray technology: hands-on approach. Wolfgang Dejan 11:30 Service & Troubleshooting. Christopher Scheer 12:00 Factory Tour. Christopher Scheer 12:45 Lunch 14:00 Practical session II: Experiments in the lab with lab and pilot equipment. Bernd Looser, Wolfgang Dejan, Tim Anders 16:00 Coffee break 16:15 Summary. Bernd Looser 16:30 Transfer to the hotel 18:45 Transfer to Workshop dinner WEDNESDAY, 20 JUNE :40 Check-out from hotel and transfer to TTC 09:00 Important parameters in processing EUDRAGIT polymers. Explaining the influence of formulation components and process parameters on the functionality of EUDRAGIT based coatings on solid dosage forms. Nina Hauschildt 10:00 Thermodynamic consideration of the film-coating process. Identifying the most crucial processing parameters, evaluating their impact on the coating result and deriving a strategy to approach an up-scaling procedure. Thorsten Cech 11:00 Coffee break 11:30 GMP compliant cleaning of pharmaceutical equipment. Outlining points to consider for the optimized cleaning of equipment in the pharmaceutical industry, including regulations, cleaning parameters, cleaning procedures and hygienic design. Jochen Berger 12:30 Summary and snack buffet 13:00 Transfer to Basel, German Railway Station (Badischer Bahnhof), Swiss Railway Station (SBB) and Euro Airport

5 ORGANIZATION TTC - Technology Training Center Regina Bernstein / Andreas Gottschalk / Bianca Nowak Werner-Glatt-Straße 1, Binzen, Germany Tel Fax Mail ttc@ttc-binzen.de LOCATION Technology Training Center, Binzen, Germany Glatt AG, Pratteln, Switzerland For further information and online registration please visit us on:

6 SPEAKERS Tim Anders Jochen Berger Thorsten Cech Wolfgang Dejan Nina Hauschildt Bernd Looser Christopher Scheer Dr. Paul Smith Glatt AG, Switzerland Ecolab (Schweiz) GmbH, Switzerland BASF SE, Germany Glatt AG, Switzerland Evonik Nutrition & Care GmbH, Germany Glatt AG, Switzerland Glatt AG, Switzerland Colorcon Ltd., UK DETAILS >> The participation fee is (exclusive of VAT). >> This fee includes participation, accompanying course notes, daytime catering and dinner. Any other expenses are to be borne by the attendee. >> Free attendance granted to a limited number of students. >> Participation is limited. Registrations will be confirmed on a first come first serve basis. >> Courses taking place in Germany are subject to Value Added Tax (VAT). >> Each participant will receive a certificate of attendance at the end of the course. >> Registration deadline: 03 May 2018

7 REGISTRATION TABLET COATING JUNE 2018 Name Company Dept. Function Address Phone Fax Yes, I want to receive information about TTC workshops in future. Signature Accomodation required from Check-in day: Check-out day: = Nights (Approx. 79,00 /night incl. breakfast)

8 Technology Training Center Regina Bernstein / Andreas Gottschalk / Bianca Nowak P.O. Box Binzen Germany