Thursday 6 July 2017, Lille, France

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1 International Society of Drug Delivery Sciences and Technology Dear Colleague, SPONSORING, EXHIBITING AND ADVERTISING OPPORTUNITIES The APGI (Association de Pharmacie Galénique Industrielle/International Society of Drug Delivery Sciences and Technology) is organizing for the first time a workshop dedicated to Oral Controlled Release Solid Dosage forms. This includes matrix systems as well as coated dosage forms, such as tablets, pellets and capsules. During the one day event, oral and poster presentations from academia and industry, practical demonstrations (in small groups) and an industrial exhibition are foreseen. As practical demonstrations are included, the maximum number of participants is limited to 150. The workshop will be held at the University of Lille, College of Pharmacy, 3 Rue du Professeur Laguesse, Lille, France. The entire spectrum, ranging from engineering aspects during the manufacturing process, the portfolio of commercially available excipients allowing to formulate a large variety of drugs, the underlying mass transport mechanisms and physical principles, characterization methods for the key properties of the devices as well as potential pitfalls and hurdles to be overcome during product development will be addressed. This workshop will give an update on the current state of the art of how to best formulate oral controlled release solid dosage forms. An overview on the available excipients, preparation techniques and apparatuses, characterization methods and future strategies will be given by world-wide leading experts in the field including: From ACADEMIA: Prof. R. Bodmeier (Freie Universitaet Berlin) on formulation strategies, Prof. T. De Beer (University of Ghent) on PAT for tabletting, Prof. J. Dressman (University of Frankfurt) on biorelevant release media, Dr. J. Goole (Free University of Brussels) on liquid oral controlled release formulations, Prof. T. Rades (University of Copenhagen) on advanced physico-chemical characterization techniques, Prof. J. Siepmann (University of Lille) on drug release mechanisms and mathematical modelling From the INDUSTRY: Dr. M. Dadparvar (Evonik) on customized release, Dr. A. Rajabi-Siahboomi (Colorcon) on controlled release matrix tablets and Dr. Klaus Wening (Gruenenthal) on tamper-resistant dosage forms. PRACTICAL DEMONSTRATIONS (in small groups) will be held on R&D tablet coating (ProCepT) Compression (Gamlen Tableting) Hot melt extrusion (Thermo Fisher Scientific) UV-imaging (Sirius Analytical) Dissolution testing (SOTAX). We would highly appreciate if your company could contribute to the meeting as a sponsor or exhibitor. Please find hereafter details on the various sponsoring/exhibiting possibilities. Your contribution will help to intensify the fruitful exchange between academia and industry and at the same time promote the awareness of your activities in the pharmaceutical field. Thank you very much in advance and looking forward to associating you with this successful event! Yours sincerely, Platinum Sponsors Prof. Juergen Siepmann President of APGI APGI International Society of Drug Delivery Sciences and Technology 5 Rue Jean-Baptiste Clément FR Châtenay-Malabry France Tel: +33 (0) Contact: Catharina Kroling, apgi.asso@u-psud.fr,

2 A SHORT PRESENTATION OF THE APGI ORGANIZER OF THE: The APGI The APGI (Association de Pharmacie Galénique Industrielle/International Society of Drug Delivery Sciences and Technology) was created in 1964 in Paris, and is an association accessible to all, academics and individuals in industry, who are concerned with pharmaceutical technology and the design, formulation and pharmacotechnical, biopharmaceutical and pharmacokinetic assessment of dosage forms and delivery systems, whether pharmaceutical or dermopharmaceutical. The APGI has members covering more than thirty different nationalities and counts contacts and friends in over fifty countries.the APGI is publishing the newsletter La Gazette. The APGI has organized (or acted as a main partner in) several major events as: The Skin and Formulation Symposium (Paris, participants, Versailles, participants, Versailles, participants, Lyon, participants) The 1 st and 2 nd Coating Workshop (Lille, participants, participants) The 1 st 2 nd Poorly Soluble Drugs Workshop (Lille, participants, participants) The World meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology co-organized with APV, Germany and A.D.R.I.T.E.L.F. - Italy (Florence, participants; Geneva, 2006, Barcelona, participants, Malta, participants, Istanbul, participants, Lisbon, participants and Glasgow, participants) The 1 st European Conference on Pharmaceutics, (Reims, France, participants. 1 st Conference on Innovation in Drug Delivery: From from biomaterials to devices (Naples, participants) 2 nd Conference on Innovation in Drug Delivery: From preformulation to development through innovative evaluation process (Aix-en-Provence, France, participants). 3 rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery (Pisa, Italy, participants) 4 th Conference on Innovation in Drug Delivery: Site-Specific Drug Delivery, (Antibes, France, 2016) The APGI was also one of the main partners in the PharmSciFair The Pharmaceutical Sciences Fair and Exhibition (Nice, participants) and PharmSciFair, Nice, 8-12 June, 2009 (850 participants) and its satellite meeting: Young Scientists Meet in Nice (230 participants) and Prague, June, 2011 (700 participants) The 11 th International Symposium on Cyclodextrins (Montpellier, participants) The Eufeps/Apgi Conference on Optimising Drug Delivery and Formulation (Versailles, 2003 and participants) The European Conference on Drug Delivery and Pharmaceutical Technology (Sevilla, Spain, participants, co-organized with the A.D.R.I.T.E.L.F. - Italy and the SEFIG - Spain)

3 PRELIMINARY ROGRAMME & REGISTRAITON FEES INVITED SPEAKERS From ACADEMIA: Prof. R. Bodmeier (Freie Universitaet Berlin) on formulation strategies Prof. T. De Beer (University of Ghent) on PAT for tabletting Prof. J. Dressman (University of Frankfurt) on bio-relevant release media Dr. J. Goole (Free University of Brussels) on liquid oral controlled release formulations Prof. T. Rades (University of Copenhagen) on advanced physico-chemical characterization techniques Prof. J. Siepmann (University of Lille) on drug release mechanisms and mathematical modelling From the INDUSTRY: Dr. M. Dadparvar (Evonik) on customized release Dr. A. Rajabi-Siahboomi (Colorcon) on controlled release matrix tablets Dr. Klaus Wening (Gruenenthal) on tamper-resistant dosage forms PRACTICAL DEMONSTRATIONS R&D tablet coating (ProCepT) Compression (Gamlen Tableting) Hot melt extrusion (Thermo Fisher Scientific) UV-imaging (Sirius Analytical) Dissolution testing (SOTAX) REGISTRATION RATES Before 31 th March, 2017 After 31 st March, 2017 APGI-Member VAT VAT Non-Member VAT* VAT* *amount including APGI membership fee for 2017 The registration fee is including lunch and coffee-breaks. French VAT: 20%

4 EXHIBITION A live exhibition is the best way to interact with your current or future customers. The Exhibition will take place in the poster, and lunch/coffee breaks area and will therefore provide you with a very a good traffic visibility. All exhibitors will be listed in the final programme and the logo of the exhibitor will be published on the website with a link to the exhibitor s website. We can propose the following options: French VAT: 20% PLATINUM SPONSORSHIP Including: - 1 table top space 6 m2 with 2 vertical display panels, 1 table, 2 chairs, electricity outlet 2 kw - 3 complimentary registrations including programme/abstract book coffee breaks and lunch - 1 full page advert - logo, company profile and acknowledgement in the programme - logo and company profile website - free distribution of company information in the Workshop wallets - logo on screen during session breaks - logo on the Apgi ings sent to addresses (3 ing) Price: 3000,00 + VAT STANDARD TABLE TOP - 2m x 2m with 2 vertical display panels, 1 table, 2 chairs, electricity outlet 2 Kw - 1 registration including programme/abstract book, coffee breaks and lunch Price: 1500,00 + VAT (extra m 2 : + 275,00 /m 2 + VAT REGISTRATION RATES FOR EXHIBITORS Full Conference fee for exhibitor. programme/abstract book, coffee breaks and lunch. Prior 31 March, 2017: 350,00 + VAT After 31 March, 2017: 450,00 + VAT Exhibitor badge for exhibitor not attending the conferences and the practical demonstrations. Including programme/abstract book, coffee breaks and lunch. Prior 31 March, 2017: 250,00 + VAT After 31 March, 2017: 300,00 + VAT Discounted rates are limited to two persons per 4 m 2 exhibition space. FLOOR PLAN: See next page

5 FLOOR PLAN

6 SPONSORING French VAT: 20% Be one of our sponsors! You can either select from one of the following three levels: PLATINUM SPONSORSHIP: Sponsorship of 3000,00 + VAT, which includes: 3 complimentary Workshop registrations including coffee breaks and lunch, and Your logo on the printed announcement (flyer), and Your logo on the up-dated pdf announcement downloadable from the APGI website but also sent regularly to a minimum of addresses, and One table top in the exhibition area (6 m 2 equipped with 2 chairs, 1 table, electricity), and A full-colour page company advertisement in the Final Programme & Abstracts Book, and Free distribution of company information in the Workshop wallets, and Your logo on screen during session breaks, and Your logo on the APGI web site: and Acknowledgement with your logo in the Final Programme & Abstracts Book GOLD SPONSORSHIP: Sponsorship of 2000,00 + VAT, which includes: 2 complimentary Workshop registrations including coffee breaks and lunch, and Your logo on the printed announcement (flyer), and Your logo on the up-dated pdf announcement downloadable from the APGI website but also sent regularly to a minimum of addresses, and A half-colour page company advertisement in the Final Programme & Abstracts Book, and Free distribution of company information in the Conference wallets, and Your logo on screen during breaks, and Your logo on the APGI web site: and Acknowledgement with your logo in the Final Programme & Abstracts Book SILVER SPONSORSHIP: Sponsorship of 1000,00 + VAT, which includes: 1 complimentary Workshop registration including coffee breaks and lunch, and Your logo on the printed announcement (flyer), and Your logo on the up-dated pdf announcement downloadable from the APGI website but also sent regularly to a minimum of addresses, and A quarter-colour page company advertisement in the Final Programme & Abstracts Book, and Your logo on screen during breaks, and Your logo on the APGI web site: and Acknowledgement with your logo in the Final Programme & Abstracts Book or sponsor a coffee break (1000,00 + VAT), or the lunch break (4000,00 + VAT). We thank you for your contribution that will help us to invite speakers and will promote your presence in the field. EXHIBITION: Exhibition rates are indicated in the order form. TERMS OF PAYMENT: All contracts once signed are deemed to be binding on both parties whether sent/received by fax or mail or electronic mail. The full value of the invoiced amount will be due on 1 April, The company logos will be displayed on the website on receipt of payment of the sponsorship. Full payment details will be included with the invoice, including the VAT payable. We will invoice you on receipt of your signed contract. French VAT: 20 %.

7 ORDER FORM Please indicate your choices, complete the form and return it to: APGI Secretariat, Attn: Mrs Catharina Kroling, 5 Rue Jean-Baptiste Clément, FR Châtenay-Malabry Cedex, France Tel +33 (06) apgi.asso@u-psud.fr No refunds after 15 April, French VAT: 20% Platinum sponsorship (3 Conference registrations; 1 table top space 6 m2 with 2 vertical display panels, 1 table, 2 chairs, electricity outlet 2 kw; 1 full page advert; logo and acknowledgement in the programme) Gold sponsorship (2 Conference registrations; 1/2 page advert; logo and acknowledgement in the programme) Silver Sponsorship (1 Conference registration; 1/4 page advert; logo and acknowledgement in the programme) Standard Table Top 2m x 2m with 2 vertical display panels, 1 table, 2 chairs, electricity outlet 2 kw, 1 registration Exhibitor badge for person not attending the conference. Including Coffee breaks (2), lunch (1) Prior 29 April, 2017 After 29 April, 2017 Full Conference fees for exhibitor. Including coffee breaks (2) and lunch (1) Prior 29 April, 2017 After 29 April, 2017 Discounted rates limited to two persons per 4 m 2 Exhibition Space (full outside back page colour) (full 3 rd page of cover colour) (inside -- full page colour) (inside -- full page b/w) (inside 1/2 page colour) (inside 1/2 page b/w) (inside - b/w - per quarter page) Sponsoring of lunch Sponsoring of one coffee break Logo on Conference Bag Insert of brochure (4 pages A4 size max) in Conference Bag Pens, Note pads and other goodies 3000,00 + VAT 2000,00 +VAT 1000,00 +VAT 1500,00 + VAT + 275,00 for extra m 2 + VAT 250,00 + VAT 300,00 + VAT 350,00 + VAT 450,00 + VAT 1300,00 + VAT 900,00 + VAT 800,00 + VAT 600,00 + VAT 500,00 + VAT 400,00 + VAT 290,00 + VAT 4000,00 + VAT 1000,00 + VAT 1000,00 + VAT 500,00 + VAT Please, contact us First name: Family name: Company: VAT No: Address: City: Zip code: Country: Tel.: Fax:

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