HANDBOOK OF NANOBIOMEDICAL RESEARCH

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1 Vol. 3 Frontiers in Nanobiomedical Research HANDBOOK OF NANOBIOMEDICAL RESEARCH Fundamentals, Applications and Recent Developments l 1 Materials for Nanomedicine

2 Frontiers in Nanobiomedical Research ISSN: Series Editors: Martin L. Yarmush (Harvard Medical School, USA) Donglu Shi (University of Cincinnati, USA) Published Vol. 1: Handbook of Immunological Properties of Engineered Nanomaterials edited by Marina A. Dobrovolskaia and Scott E. McNeil (SAIC-Frederick, Inc., USA) Vol. 2: Tissue Regeneration: Where Nano-Structure Meets Biology edited by Qing Liu (3D Biotek, USA and Tongji University, China) and Hongjun Wang (Stevens Institute of Technology, USA) Vol. 3: Handbook of Nanobiomedical Research: Fundamentals, Applications and Recent Developments (In 4 Volumes) edited by Vladimir Torchilin (Northeastern University, USA) Forthcoming titles Cancer Therapeutics and Imaging: Molecular and Cellular Engineering and Nanobiomedicine edited by Kaushal Rege (Arizona State University, USA) Nano Vaccines edited by Balaji Narasimhan (Iowa State University, USA) Nano Pharmaceuticals edited by Rajesh N. Dave (New Jersey Institute of Technology, USA) Thermal Aspects in Nanobiomedical Systems and Devices by Dong Cai (Boston College, USA) Nano Mechanochemistry in Biology edited by Jeffrey Ruberti (Northeastern University, USA) Nanomaterial Probes of Biological Processes and Systems edited by David Mast (University of Cincinnati, USA) Handbook of Biomaterials edited by Donglu Shi (University of Cincinnati, USA) and Xuejun Wen (Clemson University, USA)

3 HANDBOOK OF NANOBIOMEDICAL RESEARCH Fundamentals, Applications and Recent Developments l 1 Materials for Nanomedicine editor Vladimir Torchilin Northeastern University, USA Vol. 3 Frontiers in Nanobiomedical Research World Scientific NEW JERSEY LONDON SINGAPORE BEIJING SHANGHAI HONG KONG TAIPEI CHENNAI

4 Published by World Scientific Publishing Co. Pte. Ltd. 5 Toh Tuck Link, Singapore USA office: 27 Warren Street, Suite , Hackensack, NJ UK office: 57 Shelton Street, Covent Garden, London WC2H 9HE Library of Congress Cataloging-in-Publication Data Handbook of nanobiomedical research : fundamentals, applications, and recent developments / editor, Vladimir Torchilin. p. ; cm. -- (Frontiers in nanobiomedical research ; vol. 3) Includes bibliographical references and index. ISBN (set : alk. paper) -- ISBN (volume 1 : alk. paper) -- ISBN (volume 2 : alk. paper) -- ISBN (volume 3 : alk. paper) -- ISBN (volume 4 : alk. paper) I. Torchilin, V. P., editor. II. Series: Frontiers in nanobiomedical research ; v [DNLM: 1. Nanomedicine. 2. Nanostructures. 3. Nanotechnology. QT 36.5] R857.N dc British Library Cataloguing-in-Publication Data A catalogue record for this book is available from the British Library. Copyright 2014 by World Scientific Publishing Co. Pte. Ltd. All rights reserved. This book, or parts thereof, may not be reproduced in any form or by any means, electronic or mechanical, including photocopying, recording or any information storage and retrieval system now known or to be invented, without written permission from the publisher. For photocopying of material in this volume, please pay a copying fee through the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. In this case permission to photocopy is not required from the publisher. Typeset by Stallion Press enquiries@stallionpress.com Printed in Singapore

5 Contents Chapter 1 Liposomal Nanomedicines 1 Amr S. Abu Lila, Tatsuhiro Ishida and Theresa M. Allen Chapter 2 Solid Lipid Nanoparticles for Biomedical Applications 55 Karsten Mäder Chapter 3 Micellar Nanopreparations for Medicine 87 Rupa Sawant and Aditi Jhaveri Chapter 4 Nanoemulsions in Medicine 141 William B. Tucker and Sandro Mecozzi Chapter 5 Drug Nanocrystals and Nanosuspensions in Medicine 169 Leena Peltonen, Jouni Hirvonen and Timo Laaksonen Chapter 6 Polymeric Nanosystems for Integrated Image-Guided Cancer Therapy 199 Amit Singh, Arun K. Iyer and Mansoor M. Amiji Chapter 7 Polysaccharide-Based Nanocarriers for Drug Delivery 235 Carmen Teijeiro, Adam McGlone, Noemi Csaba, Marcos Garcia-Fuentes and María J. Alonso Chapter 8 Dendrimers for Biomedical Applications 279 Lisa M. Kaminskas, Victoria M. McLeod, Seth A. Jones, Ben J. Boyd and Christopher J. H. Porter Chapter 9 Layer-by-Layer Nanopreparations for Medicine Smart Polyelectrolyte Multilayer Capsules and Coatings 329 Rawil F. Fakhrullin, Gleb B. Sukhorukov and Yuri M. Lvov v

6 vi Contents Chapter 10 Inorganic Nanopreparations for Nanomedicine 367 James Ramos and Kaushal Rege Chapter 11 Silica-Based Nanoparticles for Biomedical Imaging and Drug Delivery Applications 403 Stephanie A. Kramer and Wenbin Lin Chapter 12 Carbon Nanotubes in Biomedical Applications 439 Krunal K. Mehta, Elena E. Paskaleva, Jonathan S. Dordick and Ravi S. Kane Chapter 13 Core-Shell Nanoparticles for Biomedical Applications 475 Mahmoud Elsabahy and Karen L. Wooley Chapter 14 Structure Activity Relationships for Tumor-Targeting Gold Nanoparticles 519 Erik C. Dreaden, Ivan H. El-Sayed and Mostafa A. El-Sayed Chapter 15 Silver Nanoparticles as Novel Antibacterial and Antiviral Agents 565 Stefania Galdiero, Annarita Falanga, Marco Cantisani, Avinash Ingle, Massimiliano Galdiero and Mahendra Rai Chapter 16 Magnetic Nanoparticles for Drug Delivery 595 Rainer Tietze, Harald Unterweger and Christoph Alexiou Chapter 17 Quantum Dots as a Platform Nanomaterial for Biomedical Applications 621 Eleonora Petryayeva, Roza Bidshahri, Kate Liu, Charles A. Haynes, Igor L. Medintz, and W. Russ Algar Index 663

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