BIOSENSING USING NANOMATERIALS

Transcription

1 BIOSENSING USING NANOMATERIALS Edited by Arben Merkogi WILEY A JOHN WILEY & SONS, INC., PUBLICATION

2 CONTENTS CONTRIBUTORS SERIES PREFACE PREFACE xi xv xvii PART I CARBON NANOTUBES 1 1. Carbon Nanotube-Based Sensors and Biosensors 3 Richard G. Compton, Gregory G. Wildgoose, and Elicia L. S. Wong 1.1. Introduction to the Structure of Carbon Nanotubes Electroanalysis Using CNT-Modified Electrodes Advantageous Application of CNTs in Sensors: ph Sensing Carbon Nanotube-Based Biosensors Using CNTs in Biosensor Production for Medical Diagnostics and Environmental Applications 25 References Isotropic Display of Biomolecules on CNT-Arrayed Nanostructures 39 Mark R. Contarino, Gary Withey, and Irwin Chaiken 2.1. Introduction: CNT Arrays for Biosensing Functionalization of CNTs: Controlling Display Through Covalent Attachment Self-Assembling Interfaces: Anchor-Probe Approach Molecular Wiring of Redox Enzymes Multiplexing Biomolecules on Nanoscale CNT Arrays Conclusions 59 References Interaction of DNA with CNTs: Properties and Prospects for Electronic Sequencing 67 Sheng Meng and Efthimios Kaxiras 3.1. Introduction Structural Properties of Combined DNA-CNT Systems Electronic Structure 79

3 VI CONTENTS 3.4. Optical Properties Biosensing and Sequencing of DNA Using CNTs Summary 92 References 93 PART II NANOPARTICLES Improved Electrochemistry of Biomolecules Using Nanomaterials 99 Jianxiu Wang, Andrew J. Wain, Xu Zhu, and Feimeng Zhou 4.1. Introduction CNT-Based Electrochemical Biosensors Nanoparticle-Based Electrochemical Biosensors Quantum Dot-Based Electrochemical Biosensors Conclusions and Outlook 123 References The Metal Nanoparticle Plasmon Band as a Powerful Tool for Chemo- and Biosensing 137 Audrey Moores and Pascal he Floch 5.1. Introduction The SPB: An Optical Property of Metal NPs Plasmon Band Variation Upon Aggregation of Nanoparticles Plasmon Band Variation on the Environment or Ligand Alteration Metal Nanoparticles as Labels Conclusions 169 References Gold Nanoparticles: A Versatile Label for Affinity Electrochemical Biosensors 177 Adriano Ambrosi, Alfredo de la Escosura-Muniz, Maria Teresa Castaneda, and Arben Merkoci 6.1. Introduction Synthesis of AuNPs Characterization of AuNPs AuNPs as Detecting Labels for Affinity Biosensors Conclusions 191 References Quantum Dots for the Development of Optical Biosensors Based on Fluorescence 199 W. Russ Algar and Ulrich J. Krull 7.1. Introduction 200

4 CONTENTS VÜ 7.2. Quantum Dots Basic Photophysics and Quantum Confinement Quantum Dot Surface Chemistry and Bioconjugation Bioanalytical Applications of Quantum Dots as Fluorescent Labels Fluorescence Resonance Energy Transfer and Quantum Dot Biosensing Summary 238 References Nanoparticle-Based Delivery and Biosensing Systems: An Example 247 Almudena Munoz Javier, Pablo del Pino, Stefan Kudera, and Wolfgang J. Parak 8.1. Introduction Functional Colloidal Nanoparticles Polyelectrolyte Capsules as a Functional Carrier System Uptake of Capsules by Cells Delivery and Sensing with Polyelectrolyte Capsules Conclusions 270 References Luminescent Quantum Dot FRET-Based Probes in Cellular and Biological Assays 275 Lifang Shi, Nitsa Rosenzweig, and Zeev Rosenzweig 9.1. Introduction Luminescent Quantum Dots Fluorescence Resonance Energy Transfer Quantum Dot FRET-Based Protease Probes Summary and Conclusions 283 References Quantum Dot-Polymer Bead Composites for Biological Sensing Applications 291 Jonathan M. Behrendt and Andrew J. Sutherland Introduction Quantum Dot-Composite Construction Applications of QD Composites Future Directions 325 References Quantum Dot Applications in Biomolecule Assays 333 Ying Xu, Pingang He, and Yuzhi Fang Introduction to QDs and Their Applications Preparation of QDs for Conjugation with Biomolecules and Cells 337

5 VIII CONTENTS Special Optoelectronic Properties in the Bioemployment of QDs Employment of QDs as Biosensing Indicators 344 References Nanoparticles and Inductively Coupled Plasma Mass Spectroscopy-Based Biosensing 355 Arben Merkoci, Roza Allabashi, and Alfredo de la Escosura-Muniz ICP-MS and Application Possibilities Detection of Metal Ions Detection of Nanoparticles Analysis of Metal-Containing Biomolecules Bioanalysis Based on Labeling with Metal Nanoparticles Conclusions 372 References 373 PART III NANOSTRUCTURED SURFACES Integration Between Template-Based Nanostructured Surfaces and Biosensors 379 Walter Vastarella, Jan Maly, Mihaela Hie, and Roberto Pilloton Introduction Nanosphere Lithography Nanoelectrodes Ensemble for Biosensing Devices Concluding Remarks 406 References Nanostructured Affinity Surfaces for MALDI-TOF-MS-Based Protein Profiling and Biomarker Discovery 421 R. M. Valiant, M. Rainer, M. Najam-Ul-Haq, R. Bakry, С Petter, N. Heigl, G. K. Bonn, and C. W. Huck Proteomics and Biomarkers MALDI in Theory and Practice Carbon Nanomaterials Near-Infrared Diffuse Reflection Spectroscopy of Carbon Nanomaterials 448 References 451 PART IV NANOPORES Biosensing with Nanopores 459 Ivan Vlassiouk and Sergei Smirnov Nanoporous Materials in Sensing 459

6 CONTENTS IX Nanochannel and Nanopore Fabrication Surface Modification Chemistry Nonelectrical Nanoporous Biosensors Electrical Nanoporous Biosensors Summary 486 References 486 INDEX 491