Global Pharma Industry Planner since 1989

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1 Connecting THE Global Pharma Industry since M e d i a Planner

2 BRANDING CAPTURING PHARMA INNOVATION FOR MORE THAN 25 YEARS Pharmaceutical Technology Europe provides objective and reliable editorial coverage of bio/pharmaceutical manufacturing, process development, regulations, quality assurance and quality control, formulation, drug delivery, API synthesis, analytical technology and testing, packaging and outsourcing. Our mission is to report on current trends and key developments in the pharmaceutical industry and publish high quality content, including peer-reviewed articles, case studies, roundtable discussions, and special features that will help our readers in their daily decision-making and in implementing best practice. AUDIENCE: CIRCULATION AND REACH Pharmaceutical Technology Europe has a qualified audience in Europe with 18,016* monthly subscribers; a figure that is qualified biannually by BPA. WHAT IS BPA? BPA Worldwide is the global industry resource for verified audience data. BPA delivers media audits of unsurpassed rigour, objectivity, accuracy, transparency and timeliness. BPA audits provide solid assurance for advertisers with rich, in-depth information about a magazine s individual subscribers. All 18,016* subscribers meet strict qualification criteria that ensure direct delivery of your advertising message to your target audience. AUDITED ELECTRONIC MEDIA PRODUCTS The BPA Brand Report includes a third-party validation of our online statistics, including our website and e-newsletters. Please refer to your copy of the BPA audit to understand how our audience is represented in Europe by location, business function and market sector. *June 2014 BPA Brand Report

3 AUdience EDITORIAL FOCUS Each issue of Pharmaceutical Technology Europe addresses a key trend in drug development, including solid dosage and parenteral manufacturing, analytical testing, equipment and processing trends, quality by design, process analytical technology, API manufacturing, formulation and drug delivery. Through expert interviews, roundtable discussions, literature reviews and survey analysis, the editors report on emerging trends, strategies and best practices in these key areas. PEER-REVIEWED RESEARCH : Quality metrics, product quality, process validation and statistical solutions. Packaging Forum: Packaging equipment, containers, systems, and materials. Facilities Design/Management: Key considerations for the design, operation and maintenance of GMP facilities. Supply Chain/Logistics: Equipment, software and services to maintain a secure and compliant serialisation programme and supply chain. Pharmaceutical Technology Europe publishes peerreviewed papers in the form of data-driven research papers, literature and patent reviews, application and technical notes and position papers on a broad range of drug development topics. All papers undergo a doubleblind peer-review process by Pharmaceutical Technology Europe s editorial advisory board, which consists of leading scientists, managers, directors and consultants. REGULATION AND COMPLIANCE KEY TOPICS : Legislation, court decisions, and regulatory changes in Europe and the United States. : Solubility and bioavailability enhancement, nanotechnology, particle design and engineering, traditional and emerging dosage forms. : Industry associations and standardsetting bodies address compendial standards and guidances. API Synthesis & : High potency, chiral chemistry, custom manufacturing, asymmetric synthesis, small- and large-molecule APIs. : Problems and solutions in equipment design and operation, and solid dosage, sterile and biopharmaceutical manufacturing. : Expert insight on analytical testing, data management, quality systems and more. : New analytical instruments, automation and process control systems, information technology tools, laboratory equipment and manufacturing equipment. BUSINESS/MARKET FOCUS Outsourcing Outlook: Trends, partnerships and business activities in the contract services market, as described by Jim Miller of PharmSource Information Services and Eric Langer, president and managing partner of BioPlan Associates. Global s: Reports from established and emerging pharmaceutical markets tackle both regulatory initiatives and market trends.

6 PHARMACEUTICAL TECHNOLOGY EUROPE 2015 EDITORIAL CALENDAR january february march april MAY JUNE Ad Close: 15 December* Ad Close: 16 January* Ad Close: 17 February* Ad Close: 16 March* Ad Close: 16 April* Ad Close: 15 May* Excipients Solid Dosage Packaging Biologics API Synthesis & Custom Outlook Aseptic Processing/Sterile Extractables and Leachables Statistical Solutions Informex USA, 3-5 Feb., New Orleans Global Drug Delivery and Formulation Summit, 9-11 Feb., Dusseldorf, Germany Pharmapack, Feb., Paris Readex Advertising Study 1/2-Page Pharmapack Exhibiitor Profile Cold Chain Analytical Testing and Instruments Particle Engineering/ Nanotechnology API Synthesis & Chiral Chemistry Solid Dosage Visual Inspection Techniques Product Quality: Biologics Biological Production Forum, 2-4 March, Dusseldorf, Germany Pittcon, 8-12 March, New Orleans BIO-Europe Spring, 9-11 March, Paris e-news Product/Service Profile Elemental Impurities Lyophilisation Semi-solid Dosage Forms API Synthesis & High-Potency Biopharmaceutical Investigations/Root Causes Facilities Design/Operations GMP Considerations in Room Design Special Themed Issue Outsourcing Issue This supplement reviews the European market for outsourcing pharmaceutical manufacturing and drug development. Articles will focus on best practices for choosing suppliers, including strategies for ensuring quality control in the supplier relationship, vendor selection, negotiating contracts, performing due diligence, technology transfer, and intellectual property protection. PDA Annual Meeting, March, Las Vegas, NV USA BDP Week, 30 March-2 April, Huntingdon Beach, CA USA 1/3 Page Product/Service Profile Process Validation Scale Up Strategies Controlled Release API Synthesis & Global API Supply Chain Equipment Design and Operation Analytical Testing for Biologics Packaging Forum Pharmapack Review INTERPHEX, April, New York e-news Product/Service Profile API Development and Transdermal Drug Delivery API Synthesis & Polymorphism and Crystallisation and DCAT Roundup Solid Dosage Data Management in Biologics Raw Materials Supply Chain/Logistics Serialisation Achema, June, Frankfurt, Germany 1/2-Page Achema Exhibiitor Profile Process Analytical Technology Biopharmaceutical Orally Inhaled and Nasal Drug Products API Synthesis & Hazardous Reagent Chemistry Aseptic Processing/Sterile Statistical Solutions Facilities Design/Operations Clean Zone Definitions BIO International Convention, June, Philadelphia 1/3 Page Product/Service Profile EDITORIAL SUBMISSIONS AND DEADLINES** Pharmaceutical Technology Europe welcomes article pitches and abstracts for regulatory, technical, and peerreviewed articles throughout the year. Submit your inquiry four months prior to publiation date. Contact Rita Peters, editorial director, to submit or for futher information.

7 PHARMACEUTICAL TECHNOLOGY EUROPE 2015 EDITORIAL CALENDAR JULY august september october november december Ad Close: 16 June* Ad Close: 16 July* Ad Close: 14 August* Ad Close: 16 September* Ad Close: 16 October* Ad Close: 16 November* Bioavailability/Solubilisation Equipment Cleaning GI Targeting API Synthesis & Process Intensification/ Continuous Flow Biopharmaceutical Operational Excellence Packaging Forum Solid Dosage Packaging Controlled Release Society, July, Edinburgh, Scotland e-news Product/Service Profile Risk Assessment and Mitigation Equipment and Trends High Potency Drug Formulation API Synthesis & Biopharmaceutical Equipment Design and Operation Lean Supply Chain/Logistics Shipping Services Special Themed Issue Pharma Development Expertise: Regional This supplement showcases the expertise of companies serving the pharmaceutical industry across Europe, with special focus on Germany, France, Italy and Benelux. Coverage includes technologies for solid dosage manufacturing, sterile fill and finish, bioprocessing and analyticaltesting. Readex Advertising Study 1/3-Page Product/Service Profile Quality by Design for Solid Dosage Room declassification in biopharma facility Taste-masking API Synthesis & Low Temperature Chemistry Aseptic Processing/Sterile Modular/Flexible Quality Metrics CPhI Worldwide, 13th -15th October, Madrid Biotechnica, 6-8 October, Hanover, Germany 1/2-Page CPhI Exhibiitor Profile Antibody Drug Conjugates Drug Reformulation Strategies API Synthesis & Fluorination Chemistry in API ß Solid Dosage Process Controls Critical Quality Attributes Packaging Forum Parenterals Packaging AAPS, Oct, Orlando e-news Product/Service Profile Continuous Solid Dosage Large Volume vs. Small Volume Parenteral Specialty Dosage Forms API Synthesis & Heterocyclic Chemistry in API Equipment Design and Operation Implementing Corrective and Preventive Action (CAPA) Supply Chain/Logistics Track and Trace 1/3-Page Product/Service Profile API Review and Outlook Emerging Therapeutics Salary and Employment Survey Combination Products Biopharmaceutical Biosimilars Product Quality: Solid/Semi-solid Dosage Facilities Design/Operations Room Pressurization Full-Page Corporate Profile Editorial content may change at the discretion of the editor. *Advertising deadlines may be subject to change. ** Receipt of an article or abstract does not guarantee inclusion in a particular issue of the magazine or on

8 DIGITAL MEDIA OPPORTUNITIES Pharmaceutical Technology Europe weekly newsletter (European audience, 11,299 recipients) Pharmaceutical Technology weekly newsletter, ept (global audience of 20,995 recipients) PT Sourcing & Management Newsletter (16,184 global manufacturing & supply chain recipients) Equipment & Processing Report showcasing processing equipment & manufacturing processes (19,891 recipients) Whitepaper alert promoting a selection of third party white papers to a high quality audience an excellent lead generation opportunity PharmTech.com Key advertising benefits: global platform, brand exposure, measurable ROI With 43,535* globally located monthly unique users, is the leading online resource for the global pharmaceutical industry. We provide a number of advertising solutions across the website including banner adverts, white papers and an on demand webinar section. PHARMACEUTICAL TECHNOLOGY NEWSLETTERS Key advertising benefits: brand exposure, targeted audience, direct delivery Pharmaceutical Technology produces a series of newsletters aimed at different job functions and geographical locations within the pharmaceutical industry. All our newsletters are requested by our audience, increasing open rates and advertisement response: WEBCASTS Pharmaceutical Technology s popular & successful webinar program is the perfect content marketing and lead generation solution for clients wishing to engage our audience, and demonstrate their expertise on a wide spectrum of topics. CAST CAST is our Custom Audience Segmentation Tool offering unparalleled access to a database of almost 1 million contacts. With CAST we can direct your marketing message to a targeted global audience of pharmaceutical industry decision makers using a number of advanced filters, ensuring your investment only reaches a relevant audience and maximising the opportunity for client conversion. We have a number of digital solutions not listed in this media planner. Please see our individual digital media planner or contact your sales representative for more information. *June 2014 BPA Brand Report

EURO PRICING 2015 PRINT DISPLAY POSITIONS (4 COLOUR) ( ) 1x 3x 6x 9x 12x 24x Full Page 7,500 6,955 6,580 6,430 6,130 5,980 2/3 Page 6,730 6,060 5,720 5,385 5,050 4,700 1/2 Page 5,230 4,710 4,450

Inside Front Cover 900 Inside Back Cover 700 Preferred Position 600 Double Page Spread 12,000 Bellyband** 9,500 Tip-on** 9,000 CLASSIFIED POSITIONS* ( ) RECRUITMENT POSITIONS ( ) MAGAZINE INSERTS ( )

9 EURO PRICING 2015 PRINT DISPLAY POSITIONS (4 COLOUR) ( ) 1x 3x 6x 9x 12x 24x Full Page 7,500 6,955 6,580 6,430 6,130 5,980 2/3 Page 6,730 6,060 5,720 5,385 5,050 4,700 1/2 Page 5,230 4,710 4,450 4,200 3,925 3,665 1/3 Page 4,100 3,700 3,495 3,300 3,080 2,880 1/4 Page 3,370 3,030 2,865 2,695 2,530 2,360 PREMIUM DISPLAY POSITIONS* ( ) SPECIAL DISPLAY POSITIONS* ( ) Outside Back Cover 1,000 Inside Front Cover 900 Inside Back Cover 700 Preferred Position 600 Double Page Spread 12,000 Bellyband** 9,500 Tip-on** 9,000 CLASSIFIED POSITIONS* ( ) RECRUITMENT POSITIONS ( ) MAGAZINE INSERTS ( ) 6 months 12 months Super Maxi Box 5,040 6,720 Maxi Box 4,115 5,430 Maxi Box 2,965 3,950 Full Page 5,245 1/2 Page 3,410 1/4 Page 2,360 Up to 20g < 5000 (Rate per 000) 800 > 5000 (Rate per 000) 690 Full Circulation (Rate per 000) 450 EURO PRICING & AD SPECS 2015 DIGITAL & WEB WEBSITE ( ) PTE WEEKLY NEWSLETTER ( ) WHITEPAPER MONTHLY NEWSLETTER ( ) Homepage per month Interstitial Pop-up Banner (640 x 480) 3,929 Peel Down 3,000 Leadboard (728 x 90) 1,857 Box (300 x 250) 1,857 Rectangle (300 x 100) 1,071 Sponsored Text 464 1x 4x Leaderboard (728 x 90) 1,130 3,990 Skyscraper (160 x 600) 920 3,255 Headline Banner (468 x 60) 840 2,940 Banner (468 x 60) 735 2,570 Product / Event Profile 655 2,310 Featured Whitepaper 1,071 WEBCASTS & SURVEYS Contact your sales representative for pricing Rates and sizes correct at time of going to press. *Premium and Special Position charges are in addition to the published print rates for Colour Display Advertising. ** Includes production and printing

10 PTE GROUP AD SIZES For all print products. Keep live matter 10 mm from all sides NON-BLEED BLEED TRIM SIZE NON-BLEED BLEED TRIM SIZE Two page spread 368 x x x 267 1/2 page horizontal 171 x x x 133 Full Page 171 x x x 267 1/3 page vertical 54 x x x 267 2/3 Page 114 x x x 267 1/3 square 114 x x x 133 1/2 Island 114 x x x 194 1/4 page 86 x x x 133 1/2 page vertical 86 x x x 267 Full page 2/3 page 1/2 page island 1/2 page vertical 1/2 page horizontal 1/3 page vertical 1/3 square 1/4 page CONTACTS Michael Tracey Publisher T E: mtracey@advanstar.com Chris Lawson Sales Manager T E: clawson@advanstar.com Christine Joinson Senior Sales Executive T E: cjoinson@advanstar.com USA SALES Paul Milazzo Director of Sales T E: pmilazzo@advanstar.com Irene Onesto Mid-West Sales Manager T E: ionesto@advanstar.com Cheryl Wall Eastern Sales Manager T E: cheryl.wall@advanstar.com Advanstar Communications (UK) Ltd Honeycomb West, Chester Business Park, Wrexham Road, Chester, CH4 9QH, UK

2018 EDITORIAL COVERAGE. Connecting the Pharma Industry for 28 Years.

2018 EDITORIAL COVERAGE. Connecting the Pharma Industry for 28 Years. 2018 EDITORIAL COVERAGE Connecting the Pharma Industry for 28 Years EDITORIAL COVERAGE: EXPERT INSIGHT AND ANALYSIS Pharmaceutical Technology Europe sets the standard for publishing independent, industry-leading