You will need to follow the instructions below and answer any questions that accompany each section being studied.
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1 Genetics Science Learning Center Internet Activity This activity has been developed to review information you have learned in previous chapters and to introduce you to information that will be studied in Chapter 14. Please type in the following internet site: You will need to follow the instructions below and answer any questions that accompany each section being studied. Click into Basic Genetics Now, scroll & click into the Build a DNA Molecule. 1. Click and Drag to build a 5 base pair DNA molecule. List your base pairs below. (use abbreviations for the base pairs) 2. Now, return to Basic Genetics and click Transcribe and Translate a Gene. Follow the instructions and list the 6 amino used in your newly created protein below. STOP 3. Next, return to the HOME PAGE and click into the Virtual Labs. Then, click into gel electrophoresis. Answer the questions below. a. What is gel electrophoresis used for? b. How is the DNA moved through the gel? c. Compare how the long strands and short strands move through the gel. d. How are the DNA strands made visible to the naked eye? 4. Continue with this simulation, but this time you will run your own gel. a. List the items needed to make a gel. b. What is agarose made from? c. What is the buffer used for? d. What is needed to set up the electrophoresis box? e. How is the buffer beneficial to the gel? f. What is needed to load the DNA into the gel?
2 g. What is the dye in the loading buffer used for? h. What is the DNA standard used for? i. What proof do you see that your electrical current is running? j. Why does the DNA move through the gel towards the positive charge at the other end? k. What is ethidium bromide used for? l. How long does it take to stain the DNA? m. Now, estimate the length of each DNA band in your sample stem Cells 5. Now, return to the HOME PAGE and click into Stem Cells and then click into The Nature of Stem Cells. Watch the video and: a. Summarize what a stem cell is and what it can do. 6. Go back and click into Unlocking Stem Cell Potential and summarize below. 7. Now, return to the HOME PAGE click into Cloning. Next, What is cloning. Answer the questions below. a. Explain cloning. b. What are the two ways cloning is done. Explain each
3 c. Now, go back and click into Click and Clone. Clone Mimi. 1. What is needed to clone Mimi? List below. 2. What must be isolated in the first step of cloning Mimi? 3. How is the egg cell prepared? 4. What needs to be done once the somatic cell and enucleated egg cell have moved to the same Petri dish? 5. Explain what it means to reprogram the DNA in the egg cell. 6. How is the egg cell stimulated to begin division? 7. What occurs after the egg cell has grown into a morula of 16 cells? 8. What color is the new baby mouse? d. Now, go back and click into Is it Cloning or Not and take the quiz. Record your answer below with cloning or not
4 Genetic Disorders There are many inherited disorders in the human population. This section covers some of these genetic disorders. Using the websites listed below, answer the following questions. Record your answers in the space provided. You do not have to memorize the frequency at which these traits occur; however, take a look at those numbers and think about how prevalent some of these traits are. Also, look at the pictures on the websites to assist in your understanding of these traits. You may be tested on these disorders. Return to the HOME PAGE and click Genetic Disorders. Next, click Chromosomal Abnormalities to answer the following questions. Click Cri-du-Chat Syndrome : 1. How is Cri du Chat inherited? 2. What is the signature characteristic of individuals afflicted with Cri du Chat? 3. What are some of the other characteristics associated with this disorder? 4. What types of tests are performed to determine if an individual has Cri du Chat? Click Klinefelter Syndrome : 5. How is Klinefelter s inherited? 6. What are some of the symptoms of Klinefelter s? 7. How is Klinfelter s diagnosed? 8. What are some of the treatments available to males with Klinefelter s? Click Down Syndrome : 1. How is Down Syndrome inherited? 2. What are some of the symptoms of Down Syndrome? 3. How is Down Syndrome diagnosed? 4. What are some of the treatments available to males with Down Syndrome?
5 Return to Genetic Disorders. Next, click Single Gene Abnormalities to answer the following questions. Click Cystic Fibrosis : 5. What is Cystic Fibrosis? 6. How do people inherit Cystic Fibrosis? 7. What are the symptoms of Cystic Fibrosis? 8. How is Cystic Fibrosis diagnosed? 9. What treatments are available to Cystic Fibrosis patients? Click Huntington s Disease : 1. What is Huntington s Disease? 2. How do people inherit Huntington s Disease? 3. What are the symptoms of Huntington s Disease? 4. How is Huntington s Disease diagnosed? 5. What treatments are available to Huntington s Disease patients?
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